Hu Wen, Jiang Hua, Chen Wei, He Sheng-Hua, Deng Bin, Wang Wen-Yuan, Wang Yan, Lu Charles Damien, Klassen Karen, Zeng Jun
West China Hospital, Sichuan University, Department of Clinical Nutrition, Chengdu, China.
Asia Pac J Clin Nutr. 2011;20(4):544-50.
Nutrition support has long been ignored in China's HIV/AIDS treatment and care. The objectives of this project were to evaluate the prevalence of malnutrition among Chengdu urban HIV positive patients, and to provide evidence for further nutritional intervention.
HIV-infected adults admitted to an infectious diseases inpatient unit were eligible for this study. Nutritional status was evaluated using Subject Global Assessment (SGA), Malnutrition Universal Screening Tool (MUST), body mass index (BMI), food frequency questionnaire and dietary records.
94 hospitalized HIV positive patients were enrolled from April 2009 to May 2010. The median CD4 T cell count was 44.0/mm3. The prevalence of malnutrition is measured by three tools and ranged from 37.2% (by BMI) to 77.2% (by SGA class B/C or MUST scores ≥ 2). Chi-square test showed significant relationship between opportunistic infections and MUST score (OR=5.67, p<0.005, 95% CI=1.96-16.4). Of patients, 59.6% had insufficient total energy intake; while 54.3% had insufficient protein intake.
Malnutrition is highly prevalent among Chengdu urban HIV/AIDS patients who underwent inpatient treatment. Calorie and protein deficiency should be given more attention in HIV/AIDS care programs. Nutrition evaluation and support should be considered an integral parts of national and community HIV/AIDS treatment and care guidelines.
在中国的艾滋病治疗与护理中，营养支持长期以来一直被忽视。本项目的目的是评估成都市区HIV阳性患者中营养不良的患病率，并为进一步的营养干预提供依据。
入住传染病住院部的HIV感染成人符合本研究条件。使用主观全面评定法（SGA）、营养不良通用筛查工具（MUST）、体重指数（BMI）、食物频率问卷和饮食记录来评估营养状况。
2009年4月至2010年5月，共纳入94例住院的HIV阳性患者。CD4 T细胞计数中位数为44.0/mm3。用三种工具测量的营养不良患病率在37.2%（按BMI）至77.2%（按SGA B/C级或MUST评分≥2）之间。卡方检验显示机会性感染与MUST评分之间存在显著关系（OR=5.67，p<0.005，95%CI=1.96-16.4）。患者中，59.6%的人总能量摄入不足；而54.3%的人蛋白质摄入不足。
在接受住院治疗的成都市区HIV/AIDS患者中，营养不良非常普遍。在艾滋病护理项目中，应更加关注热量和蛋白质缺乏问题。营养评估和支持应被视为国家和社区艾滋病治疗与护理指南的组成部分。
