Division of Gastroenterology, Department of Internal Medicine, University Hospital Center Rijeka, School of Medicine, University of Rijeka, Rijeka, Croatia.
Dig Dis. 2011;29(5):494-8. doi: 10.1159/000331518. Epub 2011 Nov 16.
Peptic ulcer bleeding is one of the most common emergency situations in medicine. Combined pharmacological and endoscopic therapy together with emerging interventional radiological procedures are successfully treating peptic ulcer disease, reserving surgical procedures for only a small portion of patients unresponsive to 'conventional' therapy. Technological advancement has seen a great improvement in the field of endoscopic treatment in the form of various methods of hemostasis. However, pharmacological therapy with proton pump inhibitors still plays the central role in the peptic ulcer bleeding treatment algorithm.
消化性溃疡出血是医学领域最常见的急症之一。联合药物治疗和内镜治疗以及新兴的介入放射学程序成功治疗了消化性溃疡病,仅将手术程序保留给一小部分对“常规”治疗无反应的患者。技术进步使内镜治疗领域在各种止血方法方面取得了巨大进步。然而,质子泵抑制剂的药物治疗在消化性溃疡出血治疗方案中仍然起着核心作用。