酷似致心律失常性右室心肌病的心脏结节病
Cardiac sarcoidosis mimicking arrhythmogenic right ventricular dysplasia.
作者信息
Steger Christina Maria, Hager Thomas, Antretter Herwig, Hoyer Hans Xaver, Altenberger Johann, Pölzl Gerhard, Müller Ludwig, Höfer Daniel
机构信息
Innsbruck Medical University, Cardiac Surgery, Anichstrasse 35, Innsbruck, 6020, Austria.
出版信息
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.08.2009.2204. Epub 2009 Nov 18.
Abstract
Isolated manifestation of sarcoidosis in the heart is very rare. The present work describes the case of a 41-year-old woman with ventricular tachycardia and severe symptoms of heart failure in June 2006. Clinical, MRI and echocardiographic findings revealed the diagnosis of an arrhythmogenic right ventricular dysplasia. Due to the severe progression of the disease, cardiac transplantation was performed in August 2007. Histopathological examination of the explanted heart, however, revealed numerous non-necrotising granulomas with giant cells, lymphocytic infiltration and interstitial fibrosis, finally confirming the diagnosis of a myocardial sarcoidosis.
摘要
结节病单独累及心脏的情况极为罕见。本研究描述了一例41岁女性患者，于2006年6月出现室性心动过速及严重心力衰竭症状。临床、磁共振成像（MRI）及超声心动图检查结果显示诊断为致心律失常性右室发育不良。由于病情严重进展，于2007年8月进行了心脏移植。然而，对切除心脏的组织病理学检查发现了大量非坏死性肉芽肿，伴有巨细胞、淋巴细胞浸润及间质纤维化，最终确诊为心肌结节病。
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