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[蒙特卡罗模拟中虚拟源构建中测量数据驱动的参数规范]

[The specification of parameters driven by measurement data in the construction of virtual sources in Monte Carlo simulation].

作者信息

Tang Bin, Gou Chengjun, Fu Yuchuan

机构信息

Radiation Physics Center, West China Hospital, Sichuan University, Chengdu 610041, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2011 Oct;28(5):932-5, 945.

PMID:22097258
Abstract

Dose calculation algorithms based on the Monte Carlo (MC) method are widely regarded as the most accurate tool available in radiotherapy. The MC simulation in radiotherapy has been split into two parts, the radiation source simulation and patient simulation. In this research, a virtual source for simulating the linear accelerator head was constructed with measurement-driven models. The dependence between the calculation accuracy and the specification of various parameters was studied by comparison between the measurement data and calculation results. It has been shown that the dose profile obtained by MC simulation can be consistent with measurement data, suggesting that the compound effect of primary photons and secondary photons are considered with appropriate parameter specification. The requirement of modeling for MC simulation can be met in clinical conditions.

摘要

基于蒙特卡罗(MC)方法的剂量计算算法被广泛认为是放射治疗中可用的最精确工具。放射治疗中的MC模拟已分为两个部分,即辐射源模拟和患者模拟。在本研究中,使用测量驱动模型构建了一个用于模拟直线加速器机头的虚拟源。通过测量数据与计算结果的比较,研究了计算精度与各种参数规格之间的依赖关系。结果表明,MC模拟获得的剂量分布可以与测量数据一致,这表明在适当的参数规格下考虑了初级光子和次级光子的复合效应。在临床条件下可以满足MC模拟的建模要求。

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