Department of Visceral Surgery and Center of Minimal-Invasive Surgery, Klinikum Siloah, Hannover, Germany.
Colorectal Dis. 2011 Nov;13 Suppl 7:63-6. doi: 10.1111/j.1463-1318.2011.02785.x.
The postoperative report of the lymph node status of colorectal cancer in clinical practice is not a given fact. Among other factors, it is dependent on the experience and technique of the surgeon as well as the pathologist. Therefore a method like sentinel lymph node biopsy (SLNB) that identifies and provides for analysis the lymph node at highest risk for tumour involvement would be highly beneficial. Unlike in breast cancer or melanoma, SLNB is more difficult to apply in colorectal cancer and is still not ready for clinical routine application for these tumor entities. However, careful patient selection and expertise of the involved specialists can improve the quality and results of SLNB in colorectal cancer. Especially in the early stage cancer patients, SLNB may be helpful to identify the earliest signs of lymphatic dissemination (thereby upstaging the patient) or to encourage a limited extent of resection.
在临床实践中，结直肠癌淋巴结状态的术后报告并不是既定事实。除其他因素外，它还取决于外科医生和病理学家的经验和技术。因此，像前哨淋巴结活检 (SLNB) 这样的方法可以识别并提供分析肿瘤最有可能受累的淋巴结，这将非常有益。与乳腺癌或黑色素瘤不同，SLNB 在结直肠癌中的应用更为困难，并且尚未准备好将其用于这些肿瘤实体的临床常规应用。然而，仔细选择患者并由专业人员进行操作，可以提高结直肠癌 SLNB 的质量和结果。特别是对于早期癌症患者，SLNB 可能有助于识别最早的淋巴扩散迹象（从而使患者分期升高）或鼓励进行有限范围的切除。
