Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Radiother Oncol. 2012 Jan;102(1):108-14. doi: 10.1016/j.radonc.2011.10.007. Epub 2011 Nov 16.
To develop a method based on electronic portal images (EPIs) for the position verification of breast cancer patients that are treated with a simultaneous integrated boost (SIB) technique.
3D setup errors of the breast outline and the thoracic wall were determined from EPIs of the tangential treatment fields and anterior posterior (AP) verification field. The method was verified with repeated CT scans of 38 patients with an average setup error larger than 5 mm.
The 3D position deviation of the boost volume can best be determined from the position deviation of the breast outline in the ventrodorsal direction and the thoracic wall in the lateral and longitudinal directions from the tangential and AP EPIs. The method gives an average overestimation of the deviation of the boost volume in the ventrodorsal, lateral and longitudinal directions by 28%, 20% and 6%, respectively and an average underestimation of the deviation of the whole breast by 32%, 17% and 39%.
The described method is superior to using tangential EPIs only and is recommended for position verification of breast cancer patients that are treated with a SIB technique if no Cone beam CT (CBCT) or fiducial markers can be used.
为了开发一种基于电子射野影像系统（EPIs）的方法，用于验证采用同步整合推量（SIB）技术治疗的乳腺癌患者的位置。
从切线治疗野和前后（AP）验证野的 EPIs 中确定乳房轮廓和胸壁的 3D 摆位误差。该方法通过对 38 例平均摆位误差大于 5 毫米的患者进行重复 CT 扫描进行了验证。
从切线和 AP EPIs 中，乳房轮廓在腹背方向和胸壁在侧方和纵向方向上的位置偏差，可以最好地确定推量体积的 3D 位置偏差。该方法平均高估了推量体积在腹背、侧方和纵向方向上的偏差分别为 28%、20%和 6%，而低估了整个乳房的偏差为 32%、17%和 39%。
如果不能使用锥形束 CT（CBCT）或基准标记，那么与仅使用切线 EPIs 相比，该描述的方法具有优越性，推荐用于采用 SIB 技术治疗的乳腺癌患者的位置验证。
