Laboratory of Toxicology and Environmental Health, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia, Spain.
Food Chem Toxicol. 2012 Feb;50(2):238-49. doi: 10.1016/j.fct.2011.11.004. Epub 2011 Nov 12.
Polybrominated diphenyl ethers (PBDEs) are a class of brominated flame retardants (BFRs) used to protect people from fires by reducing the flammability of combustible materials. In recent years, PBDEs have become widespread environmental pollutants, while body burden in the general population has been increasing. A number of studies have shown that, as for other persistent organic pollutants, dietary intake is one of the main routes of human exposure to PBDEs. The most recent scientific literature concerning the levels of PBDEs in foodstuffs and the human dietary exposure to these BFRs are here reviewed. It has been noted that the available information on human total daily intake through food consumption is basically limited to a number of European countries, USA, China, and Japan. In spite of the considerable methodological differences among studies, the results show notable coincidences such as the important contribution to the sum of total PBDEs of some congeners such as BDEs 47, 49, 99 and 209, the comparatively high contribution of fish and seafood, and dairy products, and the probably limited human health risks derived from dietary exposure to PBDEs. Various issues directly related to human exposure to PBDEs through the diet still need investigation.
多溴二苯醚（PBDEs）是一类溴化阻燃剂（BFRs），用于通过降低可燃材料的可燃性来保护人们免受火灾。近年来，PBDEs 已成为广泛的环境污染物，而普通人群的体内负担也在不断增加。许多研究表明，与其他持久性有机污染物一样，膳食摄入是人类接触 PBDEs 的主要途径之一。本文综述了最近关于食品中 PBDEs 水平以及人类对这些 BFRs 的膳食暴露的科学文献。值得注意的是，有关通过食物消费进行人类每日总摄入量的现有信息基本上仅限于一些欧洲国家、美国、中国和日本。尽管研究之间存在相当大的方法学差异，但结果显示出明显的一致性，例如某些同系物（如 BDEs 47、49、99 和 209）对总 PBDEs 总和的重要贡献、鱼类和海鲜以及奶制品的相对较高贡献，以及可能源自 PBDEs 膳食暴露的有限的人类健康风险。与通过饮食途径接触 PBDEs 有关的各种问题仍需要调查。
