Department of Pharmaceutical, Chemical and Environmental Sciences, School of Science, University of Greenwich, Medway Campus, Chatham, Kent ME4 4TB, UK.
Dent Mater. 2012 Feb;28(2):e1-5. doi: 10.1016/j.dental.2011.10.011. Epub 2011 Nov 17.
Four commercial glass-ionomer cements have been studied for their ability to take up fluoride from aqueous solution following variable maturation times in the dry at 37°C.
Sets of five specimens of four different materials were cured for times of 10 min, 24 h and 1 month, then transferred to a neutral solution of NaF at approximately 1000 ppm in fluoride. Fluoride concentration was then measured at regular time intervals up to 1 month using a fluoride ion selective electrode.
Specimens cured for 1 month showed little or no uptake over 24 h, specimens cured for 24 h showed fluctuating uptake over time, and specimens cured for 10 min showed the greatest fluoride uptake. For the latter specimens, simple kinetic models were found to apply in two cases (pseudo-first order and pseudo-second order for Chemflex and Ketac Molar Quick respectively).
The ability to take up fluoride has been shown to decline with age of cement which suggests that in clinical use glass-ionomers may become less effective at undergoing fluoride recharge than has been previously assumed.
研究了四种商业玻璃离子水门汀在 37°C 干燥条件下不同成熟时间下从水溶液中摄取氟的能力。
将四组五种不同材料的样本分别固化 10 分钟、24 小时和 1 个月,然后转移到氟浓度约为 1000ppm 的中性 NaF 溶液中。使用氟离子选择电极定期测量氟浓度,最长可达 1 个月。
固化 1 个月的样本在 24 小时内几乎没有或没有摄取,固化 24 小时的样本随时间波动摄取,固化 10 分钟的样本摄取最多。对于后者的样本,发现两种情况(化学 Flex 的拟一级和 Ketac Molar Quick 的拟二级)适用简单的动力学模型。
摄取氟的能力随水门汀年龄的增长而下降,这表明在临床应用中,玻璃离子体在经历氟再矿化方面的有效性可能比以前认为的要低。