Carey C M, Spencer M, Gove R J, Eichmiller F C
Paffenbarger Research Center, American Dental Association Foundation, National Institute of Standards and Technology, 100 Bureau Drive, Mail Stop 8546, Gaithersburg, MD 20899-8546, USA.
J Dent Res. 2003 Oct;82(10):829-32. doi: 10.1177/154405910308201013.
Fluoride is added to many dental restorative materials, including glass-ionomer cements, for the specific purpose of leaching fluoride into the surrounding tissues to provide secondary caries inhibition. During the caries process, an acidic environment attacks the dental tissues as well as the glass-ionomer cement. We hypothesized that pH significantly affects the rate of release of fluoride from the glass-ionomer cement. A continuous-flow fluoride-measuring system that monitors the amount of fluoride released over time was used to determine the release of fluoride from a resin-modified glass-ionomer cement (KetacFil). The results show that the release rate began with a fast burst of fluoride which quickly diminished to low levels in 3 days. Under neutral pH conditions, the rate of fluoride release at 72 hrs was significantly slower than at pH 4.
许多牙科修复材料都添加了氟化物，包括玻璃离子水门汀，其特定目的是使氟化物渗入周围组织，以抑制继发龋。在龋病过程中，酸性环境会侵蚀牙齿组织以及玻璃离子水门汀。我们假设pH值会显著影响玻璃离子水门汀中氟化物的释放速率。使用一个连续流动的氟化物测量系统来监测随时间释放的氟化物量，以确定树脂改性玻璃离子水门汀（KetacFil）中氟化物的释放情况。结果表明，释放速率开始时氟化物快速释放，3天内迅速降至低水平。在中性pH条件下，72小时时氟化物的释放速率明显低于pH值为4时的释放速率。
