Institute of Microbiology and Genetics, Department of Biology, Technische Universität Darmstadt, Schnittspahnstrasse 10, 64287 Darmstadt, Germany.
Biochem Soc Trans. 2011 Dec;39(6):1864-70. doi: 10.1042/BST20110713.
Bacterial MCCs (multihaem cytochromes c) represent widespread respiratory electron-transfer proteins. In addition, some of them convert substrates such as nitrite, hydroxylamine, nitric oxide, hydrazine, sulfite, thiosulfate or hydrogen peroxide. In many cases, only a single function is assigned to a specific MCC in database entries despite the fact that an MCC may accept various substrates, thus making it a multifunctional catalyst that can play diverse physiological roles in bacterial respiration, detoxification and stress defence mechanisms. The present article briefly reviews the structure, function and biogenesis of selected MCCs that catalyse key reactions in the biogeochemical nitrogen and sulfur cycles.
细菌 MCC（多血红细胞色素 c）代表广泛的呼吸电子转移蛋白。此外，它们中的一些还可以转化亚硝酸盐、羟胺、一氧化氮、肼、亚硫酸盐、硫代硫酸盐或过氧化氢等底物。在许多情况下，尽管 MCC 可能接受各种底物，但在数据库条目中仅为特定的 MCC 分配单个功能，从而使其成为多功能催化剂，可在细菌呼吸、解毒和应激防御机制中发挥多种生理作用。本文简要回顾了催化生物地球化学氮和硫循环中关键反应的选定 MCC 的结构、功能和生物发生。
