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衰老速度的个体差异在老年时更大吗?

Are individual differences in rates of aging greater at older ages?

机构信息

Department of Psychology, University of Virginia, Charlottesville, VA 22904-4400, USA.

出版信息

Neurobiol Aging. 2012 Oct;33(10):2373-81. doi: 10.1016/j.neurobiolaging.2011.10.018. Epub 2011 Nov 21.

Abstract

Although differences among people are frequently assumed to increase with age, cross-sectional comparisons of measures of brain structure and measures of cognitive functioning often reveal similar magnitudes of between-person variability across most of adulthood. The phenomenon of nearly constant variability despite systematically lower means with increased age suggests that individual differences in rates of aging may be relatively small, particularly compared with the individual differences apparent at any age. The current study examined between-person variability in cross-sectional means and in short-term longitudinal changes in 5 cognitive abilities at different ages in adulthood. The variability in both level and change in cognitive performance was found to be similar among healthy adults from 25 to 75 years of age in all 5 cognitive abilities. Furthermore, the correlations between scores at the first and second occasions were very high, and nearly the same magnitude at all ages. The results indicate that between-person differences in short-term cognitive changes are not inevitably greater among healthy older adults than among young adults.

摘要

尽管人们普遍认为人与人之间的差异会随着年龄的增长而增大,但对大脑结构测量指标和认知功能测量指标的横断面比较通常揭示了在大多数成年期内,个体间变异性的相似程度。尽管随着年龄的增长,均值系统性降低,但变异性几乎保持不变,这表明个体衰老速度的差异可能相对较小,尤其是与任何年龄的个体差异相比。本研究在不同年龄的成年人中,检验了 5 种认知能力的横断面均值和短期纵向变化的个体间变异性。在所有 5 种认知能力中,研究发现,从 25 岁到 75 岁的健康成年人的认知表现水平和变化的变异性相似。此外,第一次和第二次测试之间的得分相关性非常高,并且在所有年龄段的相关性几乎相同。研究结果表明,与年轻人相比,健康老年人短期认知变化的个体间差异不一定更大。

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