Daus W, Völcker H E, Homberg A
Universitäts-Augenklinik, Heidelberg.
Fortschr Ophthalmol. 1990;87(4):364-8.
The corneal endothelium of 17 corneal buttons with endothelial dystrophy was investigated by means of vital staining and light microscopy. Each type of dystrophy was characterized by typical morphological changes in the endothelium: in Fuch's endothelial dystrophy (n = 13), subendothelial guttata formation is characteristic; in congenital hereditary endothelial dystrophy (n = 2), a high amount of multinucleated endothelial cells was found; in posterior polymorphous dystrophy (n = 2), a multilayered endothelium was the striking feature. There is a coherent endothelial cell layer in endothelial dystrophy that may indicate a disturbance in the endothelial pump function rather than a barrier defect caused by gaps between the endothelial cells.
采用活体染色和光学显微镜对17个患有内皮营养不良的角膜植片的角膜内皮进行了研究。每种类型的营养不良都以内皮的典型形态学变化为特征：在富克斯内皮营养不良（n = 13）中，内皮下水疱形成是其特征；在先天性遗传性内皮营养不良（n = 2）中，发现大量多核内皮细胞；在后部多形性营养不良（n = 2）中，多层内皮是显著特征。在内皮营养不良中存在连贯的内皮细胞层，这可能表明内皮泵功能受到干扰，而非内皮细胞间间隙导致的屏障缺陷。
