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腹膜透析患者的日间嗜睡与生活质量

Daytime sleepiness and quality of life in peritoneal dialysis patients.

作者信息

Bilgic Ayse, Akman Beril, Sezer Siren, Arat Zubeyde, Ozelsancak Ruya, Ozdemir Nurhan

机构信息

Division of Nephrology, Faculty of Medicine, Başkent University, Ankara, Turkey.

出版信息

Ther Apher Dial. 2011 Dec;15(6):565-71. doi: 10.1111/j.1744-9987.2011.00987.x.

Abstract

We aimed to compare automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD) therapy with regard to patients' excessive daytime sleepiness (EDS) and quality of life (QOL). EDS was assessed with the Epworth Sleepiness Scale (ESS) and QOL with the Medical Outcomes Study 36-Item Short Form (SF-36) health survey. We included 59 patients (CAPD/APD, 30/29; male/female, 33/26; age, 45.3±15.8 years; dialysis duration, 42.0±33.6 months). The CAPD and APD groups were similar with respect to factors that affected sleep quality (age, sex, duration of PD), smoking, alcohol intake, socioeconomic status, body mass index, comorbid disease, and various laboratory parameters. Although one patient (3.3%) treated with CAPD and four patients (13.8%) treated with APD experienced EDS, there was no significant differences in ESS scores between the CAPD and APD patients. There was no difference in the SF-36 total and subscale scores when APD patients were compared with CAPD patients. The independent predictors of ESS were the serum albumin level (β= -2.04, P<0.01), total SF-36 score (β= 0.08, P=0.02), social functioning score (β= -2.47, P=0.01), and role-emotional subscale score (β= -1.12, P=0.05). The incidence of EDS was slightly higher in APD patients, but it did not negatively affect daily activities or QOL.

摘要

我们旨在比较自动化腹膜透析(APD)和持续非卧床腹膜透析(CAPD)治疗对患者日间过度嗜睡(EDS)和生活质量(QOL)的影响。采用Epworth嗜睡量表(ESS)评估EDS,采用医学结局研究36项简短健康调查(SF-36)评估QOL。我们纳入了59例患者(CAPD/APD,30/29;男性/女性,33/26;年龄,45.3±15.8岁;透析时间,42.0±33.6个月)。CAPD组和APD组在影响睡眠质量的因素(年龄、性别、腹膜透析时间)、吸烟、饮酒、社会经济状况、体重指数、合并症以及各种实验室参数方面相似。虽然1例接受CAPD治疗的患者(3.3%)和4例接受APD治疗的患者(13.8%)出现了EDS,但CAPD组和APD组患者的ESS评分无显著差异。将APD患者与CAPD患者进行比较时,SF-36总分及各子量表得分无差异。ESS的独立预测因素为血清白蛋白水平(β=-2.04,P<0.01)、SF-36总分(β=0.08,P=0.02)、社会功能评分(β=-2.47,P=0.01)和角色-情感子量表评分(β=-1.12,P=0.05)。APD患者中EDS的发生率略高,但对日常活动或QOL没有负面影响。

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