Gupta A K, Ahmad A J
Department of Pediatrics, JN Medical College, Aligarh Muslim University, India.
Indian Pediatr. 1990 Apr;27(4):333-7.
Using the criteria of weight(g)/height(cm)2 greater than or equal to 2.26 as cut off point, 292 (7.56%) of the 3,861 school children in the age group 5-15 years were identified as obese. The mean blood pressure levels, both systolic and diastolic, were found to be significantly higher in the obese subjects compared to the controls (p less than 0.001). Further, 10 (3.4%) of the 292 obese subjects were detected to have sustained elevations in BP levels (BP greater than mean + 2 SD for age-sex) on monthly follow-up for 6 months. On the contrary, persistent hypertension was detected in only six (0.16%) of the 3,569 controls. None of these hypertensive children had any symptoms attributable to raised blood pressures and all had only mild elevations in BP levels. Baseline investigations, carried out in 9/16 subjects, failed to document any underlying cause for hypertension. Serum cholesterol levels, however, were elevated in six subjects. This suggests a close association between childhood obesity and essential hypertension.
以体重（克）/身高（厘米）²大于或等于2.26作为切点，在3861名5至15岁的学童中，有292名（7.56%）被确定为肥胖。结果发现，肥胖受试者的收缩压和舒张压平均水平均显著高于对照组（p<0.001）。此外，在对292名肥胖受试者进行为期6个月的每月随访中，发现有10名（3.4%）受试者的血压水平持续升高（血压高于年龄-性别均值+2标准差）。相反，在3569名对照组中，仅6名（0.16%）被检测出持续性高血压。这些高血压儿童均无任何因血压升高引起的症状，且血压仅轻度升高。对16名受试者中的9名进行的基线调查未能发现高血压的任何潜在病因。然而，6名受试者的血清胆固醇水平升高。这表明儿童肥胖与原发性高血压之间存在密切关联。
