Lightowlers M W
University of Melbourne, Veterinary Clinical Centre, Werribee, Victoria, Australia.
Int J Parasitol. 1990 Jul;20(4):471-8. doi: 10.1016/0020-7519(90)90194-r.
Echinococcus spp. are the etiological agents of hydatid disease in man and other intermediate hosts. Many questions regarding the factors which determine susceptibility/resistance to hydatid disease, and the factors which influence the viability and fertility of hydatid cysts, remain to be answered. Recent research into the effects of hydatid infection on the immune system of the host has provided some insights into the host-parasite relationships. Immunochemical and recombinant DNA techniques are being applied to improve diagnosis of hydatidosis in man and E. granulosus infection in dogs, and also in the development of vaccines against infection with taeniid cestode larvae. The successes which have been achieved in these areas are likely to provide valuable tools for the control of cystic hydatidosis in man. These recent studies in the areas of immunobiology, serological diagnosis and vaccination are reviewed.
棘球绦虫属是人类和其他中间宿主中包虫病的病原体。关于决定对包虫病易感性/抗性的因素以及影响包虫囊肿活力和繁殖力的因素，仍有许多问题有待解答。最近对包虫感染对宿主免疫系统影响的研究为宿主-寄生虫关系提供了一些见解。免疫化学和重组DNA技术正被应用于改善人类包虫病和犬类细粒棘球绦虫感染的诊断，以及开发针对带绦虫幼虫感染的疫苗。在这些领域所取得的成功可能为控制人类囊型包虫病提供有价值的工具。本文对免疫生物学、血清学诊断和疫苗接种等领域的这些最新研究进行了综述。
