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顺铂经肝动脉化疗后切除孤立性异时性肝癌淋巴结转移:一例报告。

Resection of solitary metachronous lymph node metastasis from hepatocellular carcinoma following transarterial chemotherapy with cisplatin: a case report.

机构信息

Department of Digestive Surgery, Nihon University School of Medicine, 30-1 Oyaguchikami-machi, Itabashi-ku, Tokyo 173-8610, Japan.

出版信息

Anticancer Res. 2011 Nov;31(11):3991-3.

PMID:22110232
Abstract

A 74-year-old female was found to have a 40-mm liver tumor (in segment VIII) by ultrasonography and was diagnosed with hepatocellular carcinoma (HCC). She underwent liver resection and was stably treated without recurrence for 19 months. A 45-mm extrahepatic tumor was then found during follow-up with enhanced computed tomography and was diagnosed as being a metachronous lymph node (LN) metastasis. Angiography revealed that the metastasis LN was fed by both the right and left gastric arteries. Transarterial chemotherapy with cisplatin was scheduled to control LN metastasis and to prevent intrahepatic metastasis, simultaneously. Blood alteration using coil embolization was performed to isolate the feeding arteries before transarterial chemotherapy with cisplatin powder. The patient was stably treated for 6 months (3 times) and no new intra- or extrahepatic metastatic lesions appeared during the chemotherapy. The patient subsequently underwent systematic LN dissection of the porta hepatis. She was successfully treated, and has remained recurrence-free for almost 5 years.

摘要

一位 74 岁女性因超声检查发现肝脏 40mm 肿瘤(VIII 段)而被诊断为肝细胞癌(HCC)。她接受了肝切除术,19 个月来无复发,病情稳定。在后续的增强 CT 检查中发现一个 45mm 的肝外肿瘤,被诊断为同时性淋巴结(LN)转移。血管造影显示转移的 LN 由胃左动脉和胃右动脉共同供血。为了控制 LN 转移并预防肝内转移,计划进行顺铂经动脉化疗。在使用顺铂粉末进行经动脉化疗之前,使用线圈栓塞进行血液改变以隔离供血动脉。该患者接受了 6 个月(3 次)的稳定治疗(3 次),在化疗期间没有出现新的肝内或肝外转移病灶。随后,该患者接受了系统性肝门淋巴结清扫术。她成功地接受了治疗,近 5 年来一直没有复发。

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Resection of solitary metachronous lymph node metastasis from hepatocellular carcinoma following transarterial chemotherapy with cisplatin: a case report.顺铂经肝动脉化疗后切除孤立性异时性肝癌淋巴结转移:一例报告。
Anticancer Res. 2011 Nov;31(11):3991-3.
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引用本文的文献

1
Solitary Metastasis to a Distant Lymph Node in the Descending Mesocolon After Primary Resection for Hepatocellular Carcinoma: Is Surgical Resection Valid?肝细胞癌初次切除术后降结肠系膜孤立性远处淋巴结转移:手术切除是否有效?
Am J Case Rep. 2016 Dec 1;17:909-915. doi: 10.12659/ajcr.900813.
2
Metastatic recurrence to a solitary lymph node four years after hepatic lobectomy for primary hepatocellular carcinoma.原发性肝细胞癌肝叶切除术后四年出现孤立淋巴结转移复发。
World J Hepatol. 2016 Aug 18;8(23):994-8. doi: 10.4254/wjh.v8.i23.994.
3
Complete remission by transarterial infusion with cisplatin for recurrent bile duct tumor thrombus of hepatocellular carcinoma: report of a case.
经动脉顺铂灌注治疗复发性肝癌胆管癌栓完全缓解 1 例报告。
World J Surg Oncol. 2013 Mar 23;11:78. doi: 10.1186/1477-7819-11-78.