使用承诺问卷评估健康研究对象和乳腺疾病及乳腺癌患者的“癌症易患人格”特征：芬兰的前瞻性病例对照研究。

Assessment of 'cancer-prone personality' characteristics in healthy study subjects and in patients with breast disease and breast cancer using the commitment questionnaire: a prospective case-control study in Finland.

机构信息

Department of Surgery, Kuopio University Hospital, PL 1777, 70211 Kuopio, Finland.

出版信息

Anticancer Res. 2011 Nov;31(11):4013-7.

Abstract

BACKGROUND

The findings of a repressed expression of emotions in cancer patients contributed to the hypothesis developed by Lydia Temoshok of a type C personality ('cancer-prone'). To the Authors' knowledge, the associations between the 'cancer-prone personality' characteristics in commitment test and the risk of breast cancer (BC) have rarely been considered together in a prospective study.

PATIENTS AND METHODS

In an extension of the Kuopio Breast Cancer Study, 115 women with breast symptoms were evaluated for commitment test before any diagnostic procedures were carried out.

RESULTS

The clinical examination and biopsy showed BC in 34 patients, benign breast disease (BBD) in 53 patients and 28 individuals were shown to be healthy study subjects (HSS). The BC group reported significantly more commitment to own children (Function A) (mean Commitment score, 3.14) than the patients in the BBD group (mean Commitment score, 3.51) and in the HSS group (mean Commitment score, 3.77) (p=0.05). The women in the BC group also reported more commitment to own husband (Function B) (mean Commitment score, 3.30) than the patients in the BBD group (mean Commitment score, 3.83) and the patients in the HSS group (mean Commitment score, 3.76). The BC group reported significantly more commitment to own work and own body (Function D and G) (mean Commitment scores, 3.20 and 3.50) than the patients in the BBD group (mean Commitment scores, 3.75 and 3.71) or HSS group (mean Commitment scores, 3.46 and 3.50). The mean sum (mean, SD) of the scores were significantly lower in the BC group (31.1, 5.8) than in the BBD (35.2, 6.9) and HSS group (36.4, 5.6) (p=0.02), showing more commitment in the BC group.

CONCLUSION

In summary, patients with BC tended to have an increased risk for bearing the 'high commitment' characteristic and this pattern could contribute to cancer risk through immune and hormonal pathways.

摘要

背景

癌症患者情绪表达受抑制的发现促成了莉迪亚·特莫肖克（Lydia Temoshok）提出的 C 型人格（“癌症易患型”）假说。据作者所知，承诺测试中的“癌症易患型人格”特征与乳腺癌（BC）风险之间的关联很少在前瞻性研究中一起考虑。

患者和方法

在库奥皮奥乳腺癌研究的扩展中，对 115 名有乳房症状的女性进行了承诺测试评估，然后再进行任何诊断程序。

结果

临床检查和活检显示 34 名患者患有 BC，53 名患者患有良性乳腺疾病（BBD），28 名个体被证明是健康研究对象（HSS）。BC 组报告对自己孩子的承诺明显更多（功能 A）（承诺平均得分 3.14），而 BBD 组（承诺平均得分 3.51）和 HSS 组（承诺平均得分 3.77）（p=0.05）。BC 组报告对自己丈夫的承诺也更多（功能 B）（承诺平均得分 3.30），而 BBD 组（承诺平均得分 3.83）和 HSS 组（承诺平均得分 3.76）。BC 组报告对自己工作和自己身体的承诺明显更多（功能 D 和 G）（承诺平均得分 3.20 和 3.50），而 BBD 组（承诺平均得分 3.75 和 3.71）或 HSS 组（承诺平均得分 3.46 和 3.50）。BC 组的平均总分（平均值，标准差）明显低于 BBD 组（31.1，5.8）和 HSS 组（36.4，5.6）（p=0.02），表明 BC 组的承诺更高。