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慢性直肠痛和慢性盆腔疼痛综合征:新的病因学见解和治疗选择。

Chronic proctalgia and chronic pelvic pain syndromes: new etiologic insights and treatment options.

出版信息

World J Gastroenterol. 2011 Oct 28;17(40):4447-55. doi: 10.3748/wjg.v17.i40.4447.

Abstract

This systematic review addresses the pathophysiology, diagnostic evaluation, and treatment of several chronic pain syndromes affecting the pelvic organs: chronic proctalgia, coccygodynia, pudendal neuralgia, and chronic pelvic pain. Chronic or recurrent pain in the anal canal, rectum, or other pelvic organs occurs in 7% to 24% of the population and is associated with impaired quality of life and high health care costs. However, these pain syndromes are poorly understood, with little research evidence available to guide their diagnosis and treatment. This situation appears to be changing: a recently published large randomized, controlled trial by our group comparing biofeedback, electrogalvanic stimulation, and massage for the treatment of chronic proctalgia has shown success rates of 85% for biofeedback when patients are selected based on physical examination evidence of tenderness in response to traction on the levator ani muscle--a physical sign suggestive of striated muscle tension. Excessive tension (spasm) in the striated muscles of the pelvic floor appears to be common to most of the pelvic pain syndromes. This suggests the possibility that similar approaches to diagnostic assessment and treatment may improve outcomes in other pelvic pain disorders.

摘要

本系统评价旨在探讨影响盆腔器官的几种慢性疼痛综合征(慢性直肠痛、尾骨痛、阴部神经痛和慢性盆腔痛)的病理生理学、诊断评估和治疗。7%至 24%的人群会出现肛门、直肠或其他盆腔器官的慢性或复发性疼痛,这与生活质量受损和高额医疗费用有关。然而,这些疼痛综合征的发病机制尚未完全阐明,针对其诊断和治疗的研究证据也十分有限。这种情况似乎正在发生变化:我们小组最近发表了一项大型随机对照试验,比较了生物反馈、电刺激和按摩治疗慢性直肠痛的效果。结果显示,对于通过提肛肌触诊检查发现对牵引有压痛的患者,生物反馈的成功率为 85%,这种物理征象提示横纹肌张力增加。盆底横纹肌张力过高(痉挛)似乎是大多数盆腔疼痛综合征的共同特征。这表明,类似的诊断评估和治疗方法可能会改善其他盆腔疼痛疾病的预后。

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