Lee Eugene W, Huang William C
Department of Urology, New York University School of Medicine, NY 10016, USA.
Prostate Cancer. 2011;2011:394182. doi: 10.1155/2011/394182. Epub 2010 Dec 5.
Traditionally, the patient with a new diagnosis of localized prostate cancer faces either radical therapy, in the form of surgery or radiation, or active surveillance. A growing subset of these men may not be willing to accept the psychological burden of active surveillance nor the side effects of extirpative or radiation therapy. Local ablative therapies including cryotherapy, high-intensity focused ultrasound, and vascular-targeted photodynamic therapy have emerged as a means for minimally invasive definitive treatment. These treatments are well tolerated with decreased morbidity in association with improvements in technology; however, long-term oncologic efficacy remains to be determined.
传统上，新诊断为局限性前列腺癌的患者面临着根治性治疗（手术或放疗形式）或主动监测。这些患者中越来越多的一部分可能不愿意接受主动监测带来的心理负担，也不愿接受切除性或放射治疗的副作用。包括冷冻疗法、高强度聚焦超声和血管靶向光动力疗法在内的局部消融疗法已成为微创根治性治疗的一种手段。随着技术的进步，这些治疗耐受性良好，发病率降低；然而，长期肿瘤疗效仍有待确定。
