免疫组织化学在皮肤附属器肿瘤诊断中的作用。

Role of immunohistochemistry in diagnosing tumors of cutaneous appendages.

作者信息

Hoang Mai P

机构信息

Harvard Medical School, and Massachusetts General Hospital, Boston, MA 02114, USA.

出版信息

Am J Dermatopathol. 2011 Dec;33(8):765-71; quiz 772-4. doi: 10.1097/DAD.0b013e31820a4837.

DOI:10.1097/DAD.0b013e31820a4837

PMID:22112636

Abstract

In recent years, there has been significant progress in immunohistochemistry as an ancillary tool in diagnostic dermatopathology. In most instances, the histologic diagnosis can be rendered with the routine histologic sections; however, immunohistochemistry can help to narrow the differential in diagnosing neoplasms of cutaneous appendages in some settings including adnexal versus epidermal origin, benign versus malignant adnexal neoplasms, and primary adnexal carcinoma versus cutaneous metastases as outlined in this review.

摘要

近年来，免疫组织化学作为诊断皮肤病理学的辅助工具取得了显著进展。在大多数情况下，常规组织学切片即可做出组织学诊断；然而，如本综述所述，在某些情况下，免疫组织化学有助于缩小皮肤附属器肿瘤诊断的鉴别范围，包括附属器与表皮来源、良性与恶性附属器肿瘤，以及原发性附属器癌与皮肤转移瘤。