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膝关节巨大关节内滑膜外骨软骨瘤:两例报告

Giant intra-articular extrasynovial osteochondroma of the knee: a report of two cases.

作者信息

De Maio F, Bisicchia S, Potenza V, Caterini R, Farsetti P

机构信息

Department of Orthopaedic Surgery, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy.

出版信息

Open Orthop J. 2011;5:368-71. doi: 10.2174/1874325001105010368. Epub 2011 Nov 4.

Abstract

We report two cases of a giant extrasynovial osteochondroma of the knee located in the infrapatellar fat pad region, in two females who were 58 and 71 years old respectively. Both patients had noticed the mass many years before our first clinical observation. In both patients, at physical examination a solid, firm and hard mass was palpable in the anterior part of the knee in Hoffa's fat pad region, and the range of motion of the knee was severely restricted and painful. CT scan examination with 3D-reconstruction showed two large, calcified neoformations behind the patellar tendon, between the apex of the patella and the proximal third of the tibia. In both cases, the mass was completely resected surgically through an anterior longitudinal approach. At histological examination, the excised masses consisted of an outer layer of hyaline cartilage without significant chondrocyte atypia and an inner region of bone trabeculae formed by endochondral ossification. At follow-up, 8 and 4 years after the operation, both patients were pain-free, with complete recovery of the range of motion of the knee and without any clinical or radiographic evidence of recurrence. The authors believe that intra-articular extrasynovial osteochondroma of the knee is a primary metaplasia of Hoffa's fat pad. Usually, the tumor develops slowly and asymptomatically over many years. The treatment of choice is a marginal resection of the mass, although a biopsy should be considered in some cases. Recurrences are extremely rare.

摘要

我们报告了两例位于髌下脂肪垫区域的膝关节巨大滑膜外骨软骨瘤病例,患者分别为两名女性,年龄分别为58岁和71岁。两名患者在我们首次临床观察前多年就已注意到肿块。两名患者在体格检查时,均在霍法脂肪垫区域的膝关节前部可触及一个坚实、坚硬的肿块,膝关节活动范围严重受限且疼痛。CT扫描三维重建显示,在髌腱后方、髌骨尖与胫骨近端三分之一之间有两个大的钙化新生物。在这两例病例中,均通过前纵行入路手术完整切除了肿块。组织学检查显示,切除的肿块由一层无明显软骨细胞异型性的透明软骨外层和一个由软骨内成骨形成的骨小梁内部区域组成。随访时,术后8年和4年,两名患者均无疼痛,膝关节活动范围完全恢复,且无任何临床或影像学复发证据。作者认为,膝关节关节内滑膜外骨软骨瘤是霍法脂肪垫的一种原发性化生。通常,肿瘤多年来发展缓慢且无症状。治疗的选择是肿块边缘切除,不过在某些情况下应考虑进行活检。复发极为罕见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769b/3219887/f8d6b0c9a164/TOORTHJ-5-368_F1.jpg

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