O'Connell Lauren, Memon Adeel R, Foran Paul, Leen Eamon, Kenny Patrick J
Connolly Hospital Blanchardstown, Dublin, Ireland.
Connolly Hospital Blanchardstown, Dublin, Ireland.
Int J Surg Case Rep. 2017;32:80-82. doi: 10.1016/j.ijscr.2017.01.005. Epub 2017 Jan 5.
Synovial chrondomatosis is a rare disorder characterised by the development of hyaline cartilage from the synovial membrane. Large isolated lesions in the Hoffa's fat pad are an uncommon entity.
A 33 year old gentleman presented complaining of progressive knee pain associated with an enlarging lesion on the anterior aspect of the right knee, with associated locking and giving way. Examination revealed a firm 4×5cm lesion adjacent to the patellar tendon. Subsequent CT and MRI demonstrated a lesion in the inferior aspect of Hoffa's fat pad, with a second lesion adjacent to the proximal tibiofibular joint, in addition to advanced degenerative changes and a meniscal tear. He proceeded to excisional biopsy. Histological analysis was consistent with a solitary synovial osteochondroma. There were no atypical features suggestive of malignancy.
Synovial chondromatosis is a rare disorder affecting the synovial joints. The underlying pathophysiology is thought to be metaplastic change of the synovium to hyaline cartilaginous tissue. Transformation to malignancy has been described but is uncommon with an estimated risk of 5%. It is 1.5-2 times as prevalent in males versus females. Symptoms which patients may complain of include pain;locking and giving way; and palpable masses. The management usually entails removal of the mass lesion with or without accompanying synovectomy. Recurrence of disease may occur in up to 15-23% of patients.
Synovial chrondromatosis is a rare but well recognised condition. Long term follow up is advised in view of the risk of recurrence and malignant transformation.
滑膜软骨瘤病是一种罕见的疾病,其特征是滑膜形成透明软骨。 Hoffa脂肪垫内的孤立性大病灶是一种不常见的情况。
一名33岁男性患者因右膝前部逐渐加重的疼痛伴病灶增大、关节交锁及打软腿前来就诊。检查发现髌腱旁有一个质地硬的4×5cm病灶。随后的CT和MRI显示Hoffa脂肪垫下方有一个病灶,胫腓近侧关节旁还有一个病灶,此外还有严重的退行性改变和半月板撕裂。患者接受了切除活检。组织学分析符合孤立性滑膜骨软骨瘤。没有提示恶性肿瘤的非典型特征。
滑膜软骨瘤病是一种影响滑膜关节的罕见疾病。其潜在的病理生理学被认为是滑膜向透明软骨组织的化生改变。已描述有恶变情况,但不常见,估计风险为5%。男性发病率是女性的1.5 - 2倍。患者可能出现的症状包括疼痛、关节交锁及打软腿和可触及肿块。治疗通常包括切除肿块病灶,可伴或不伴滑膜切除术。高达15 - 23%的患者可能会复发。
滑膜软骨瘤病是一种罕见但已被充分认识的疾病。鉴于有复发和恶变风险,建议进行长期随访。