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针对动脉瘤和闭塞性疾病的择期主动脉重建术的当前结果。

Current results of elective aortic reconstruction for aneurysmal and occlusive disease.

作者信息

Clark E T, Gewertz B L, Bassiouny H S, Zarins C K

机构信息

Department of Surgery, University of Chicago, IL.

出版信息

J Cardiovasc Surg (Torino). 1990 Jul-Aug;31(4):438-41.

PMID:2211795
Abstract

Decisions to resect small aortic aneurysms or employ non-operative treatment for aorto-iliac occlusive disease must depend on current rather than historical surgical results. To assess current morbidity and mortality, we reviewed 200 consecutive aortic resections in two groups of patients treated from 1981 to 1989: those undergoing elective aortofemoral bypass for occlusive disease (AFB, no. 100) or resection of infrarenal abdominal aortic aneurysms (AAA, no. 100). Indications for AFB included claudication (54%), rest pain (32%), and gangrene (13%). AAA size ranged from 3 to 14 cm (mean 6.5 +/- 2.4 cm); 45% presented with abdominal or back pain. Patients undergoing AFB were younger (AFB 61.5 +/- 10 years vs AAA 68.7 +/- 8.9 years) with a higher incidence of some atherosclerotic risk factors, diabetes mellitus 30% vs 10%, tobacco use 77% vs 49%, hyperlipidemia 21% vs 7%; p less than 0.001). Coronary artery disease (CAD) was more prevalent in AAA patients (49% vs 34%; p less than 0.001). Postoperative mortality was not different in occlusive or aneurysmal disease (3% AFB vs 2% AAA), nor was the occurrence of serious complications such as myocardial infarction (2% vs 1%) or pulmonary embolism (2% vs 3%). Improvements in patient selection, perioperative care and surgical technique have lowered the mortality of elective aortic surgery. Given the current standard of care, an aggressive approach to AAA even in high risk patients is appropriate. The low morbidity of AFB for occlusive disease mandates a critical appraisal of less effective nonoperative therapies.

摘要

决定是否切除小主动脉瘤或采用非手术治疗方法治疗主-髂动脉闭塞性疾病必须依据当前而非以往的手术结果。为评估当前的发病率和死亡率,我们回顾了1981年至1989年期间接受治疗的两组患者的200例连续主动脉手术:一组是因闭塞性疾病接受择期主-股动脉旁路移植术的患者(AFB,100例),另一组是接受肾下腹主动脉瘤(AAA)切除术的患者(100例)。AFB的适应证包括间歇性跛行(54%)、静息痛(32%)和坏疽(13%)。AAA大小范围为3至14厘米(平均6.5±2.4厘米);45%的患者表现为腹痛或背痛。接受AFB的患者更年轻(AFB组61.5±10岁,AAA组68.7±8.9岁),某些动脉粥样硬化危险因素的发生率更高,糖尿病分别为30%和10%,吸烟分别为77%和49%,高脂血症分别为21%和7%;p<0.001)。冠状动脉疾病(CAD)在AAA患者中更为普遍(49%对34%;p<0.001)。闭塞性疾病或动脉瘤性疾病的术后死亡率没有差异(AFB组为3%,AAA组为2%),心肌梗死(2%对1%)或肺栓塞(2%对3%)等严重并发症的发生率也没有差异。患者选择、围手术期护理和手术技术的改进降低了择期主动脉手术的死亡率。鉴于当前的护理标准,即使是高危患者,对AAA采取积极的治疗方法也是合适的。AFB治疗闭塞性疾病的低发病率要求对效果较差的非手术治疗进行严格评估。

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