Jaakkola P, Hippeläinen M, Oksala I
Department of Surgery, Kuopio University Hospital, Finland.
Ann Chir Gynaecol. 1996;85(1):28-35.
330 patients operated on for infrarenal abdominal aortic aneurysm (AAA) or aortoiliac occlusive disease (AIOD) between 1976-85 were retrospectively reviewed for early mortality and long-term survival. Data were analysed by crosstabulation and stepwise logistic regression methods for early mortality and by Kaplan-Meyer and Cox proportional hazard model for late survival. The 30-day mortality for elective AAA-patients was 9.6% and for ruptures 64.6%. For the AIOD-patients it was 2.0%. The principal cause of early death in the elective patients was acute myocardial infarction. The five-year survival rates for elective and ruptured AAA and AIOD-patients were 68%, 56% and 74%, respectively. The major late cause of death was coronary heart disease followed by pulmonary cancer. The risk factors for 30-day mortality were coronary heart disease, rupture, preoperative shock, excessive bleeding and aortic crossclamping time for the AAA-patients. In the rupture group the specialization of the surgeon had a significant impact on early mortality. Factors affecting the late survival were age, chronic cardiac failure, operation year, chronic pulmonary disease and previous malignancy in the whole study population. The late survival of both AAA and AIOD-patients after a successful operation was significantly shorter than that of an age- and sexmatched normal population. The late survival of AAA-patients was worse than that of AIOD-patients.
对1976年至1985年间接受肾下腹主动脉瘤(AAA)或主-髂动脉闭塞性疾病(AIOD)手术的330例患者进行回顾性研究,以分析早期死亡率和长期生存率。采用交叉表法和逐步逻辑回归法分析早期死亡率数据,采用Kaplan-Meyer法和Cox比例风险模型分析晚期生存率数据。择期AAA患者的30天死亡率为9.6%,破裂性AAA患者为64.6%。AIOD患者的30天死亡率为2.0%。择期手术患者早期死亡的主要原因是急性心肌梗死。择期、破裂性AAA患者和AIOD患者的五年生存率分别为68%、56%和74%。晚期死亡的主要原因是冠心病,其次是肺癌。AAA患者30天死亡率的危险因素包括冠心病、破裂、术前休克、出血过多和主动脉阻断时间。在破裂组中,外科医生的专业水平对早期死亡率有显著影响。在整个研究人群中,影响晚期生存的因素包括年龄、慢性心力衰竭、手术年份、慢性肺病和既往恶性肿瘤。成功手术后,AAA患者和AIOD患者的晚期生存率均显著低于年龄和性别匹配的正常人群。AAA患者的晚期生存率低于AIOD患者。