Galushko S V, Shishkina I P, Soloshonok V A, Kukhar V P
Institute of Bioorganic Chemistry, Academy of Sciences of the Ukrainian SSR, Kiev.
J Chromatogr. 1990 Jul 6;511:115-21. doi: 10.1016/s0021-9673(01)93276-5.
The chromatographic behaviour of some alpha-trifluoromethyl-alpha-aminoacids on L-proline- and L-hydroxyproline sorbents was studied. The retention and selectivity parameters of the separation of amino acid enantiomers on the sorbents were determined. The introduction of a CF3 [corrected] group led to an increased selectivity in the separation of amino acid enantiomers on a proline sorbent and to a decreased selectivity on a hydroxyproline sorbent.
研究了一些α-三氟甲基-α-氨基酸在L-脯氨酸和L-羟脯氨酸吸附剂上的色谱行为。测定了氨基酸对映体在这些吸附剂上分离的保留和选择性参数。引入CF3基团导致脯氨酸吸附剂上氨基酸对映体分离的选择性增加，而在羟脯氨酸吸附剂上选择性降低。
