Department of Biomedical Engineering, Duke University, Durham, NC 27708-0281, USA.
J Biomech. 2012 Jan 10;45(2):386-9. doi: 10.1016/j.jbiomech.2011.10.029. Epub 2011 Nov 26.
Investigations of biomechanical properties of pediatric cadaver cervical spines subjected to tensile or bending modes of loading are generally limited by a lack of available tissue and limiting sample sizes, both per age and across age ranges. It is therefore important to develop fixation techniques capable of testing individual cadavers in multiple modes of loading to obtain more biomechanical data per subject. In this study, an experimental apparatus and fixation methodology was developed to accommodate cadaver osteoligamentous head-neck complexes from around birth (perinatal) to full maturation (adult) [cervical length: 2.5-12.5 cm; head breadth: 6-15 cm; head length: 6-19 cm] and sequentially test the whole cervical spine in tension, the upper cervical spine in bending and the upper cervical spine in tension. The experimental apparatus and the fixation methodology provided a rigid casting of the head during testing and did not compromise the skull. Further testing of the intact skull and sub-cranial material was made available due to the design of the apparatus and fixation techniques utilized during spinal testing. The stiffness of the experimental apparatus and fixation technique are reported to better characterize the cervical spine stiffness data obtained from the apparatus. The apparatus and fixation technique stiffness was 1986 N/mm. This experimental system provides a stiff and consistent platform for biomechanical testing across a broad age range and under multiple modes of loading.
研究人员在对儿童尸体颈椎进行拉伸或弯曲加载模式的生物力学特性研究时,通常受到可用组织的缺乏和样本量的限制,包括每个年龄段和跨年龄段的样本量。因此,开发能够在多种加载模式下测试单个尸体的固定技术以获得更多的生物力学数据是很重要的。在这项研究中,开发了一种实验设备和固定方法,以适应从出生前(围产期)到完全成熟(成人)的尸体骨-韧带头-颈复合体[颈椎长度:2.5-12.5 厘米;头部宽度:6-15 厘米;头部长度:6-19 厘米],并依次对整个颈椎进行拉伸、上颈椎进行弯曲和上颈椎进行拉伸测试。实验设备和固定方法在测试过程中为头部提供了刚性的铸造,并且不会损坏颅骨。由于在脊柱测试过程中使用的设备和固定技术的设计,因此可以进一步测试完整的颅骨和颅下材料。实验设备和固定技术的刚度被报道可以更好地描述从设备获得的颈椎刚度数据。该设备和固定技术的刚度为 1986N/mm。该实验系统为在广泛的年龄范围内和多种加载模式下进行生物力学测试提供了一个坚固且一致的平台。