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术后心房颤动与中风风险或移植物类型和数量的增加无关:一项单中心回顾性分析。

Postoperative atrial fibrillation is not associated with an increase risk of stroke or the type and number of grafts: a single-center retrospective analysis.

机构信息

Department of Cardiology, Baystate Medical Center, Springfield, Massachusetts 01199, USA.

出版信息

Clin Cardiol. 2011 Dec;34(12):787-90. doi: 10.1002/clc.21001. Epub 2011 Nov 28.

Abstract

BACKGROUND

Atrial fibrillation (AF) and atrial flutter are the 2 most common types of dysrhythmia in patients undergoing coronary artery bypass graft (CABG) surgery and are associated with increased morbidity and mortality. We sought to explore the association between the type and quantity of bypass grafts and cardiovascular outcomes in patients with postoperative AF (POAF).

HYPOTHESIS

The type and quantity of bypass grafts is associated with POAF.

METHODS

We queried the Society of Thoracic Surgery National Database for CABG operations, both with and without valve procedures, performed at Baystate Medical Center between January 2002 and July 2007. We used multivariable logistic regression modeling to identify predictors of POAF and to explore the impact of AF on major adverse cardiac outcomes in this post-CABG population.

RESULTS

A total of 3068 patients received CABG surgery, 187 (6.1%) of whom received concurrent valve replacement or repair. The incidence of POAF was 38.3%. POAF was significantly associated with readmission within 30 days (P < 0.009), increased length of stay (P << 0.0001), and a strong trend toward increased 30 day mortality (P = 0.058). There was no association between POAF and postoperative stroke (P = 0.92), graft type (P = nonsignificant) or number of grafts (P = nonsignificant).

CONCLUSIONS

Patients with POAF experienced increased morbidity and mortality as demonstrated by previous studies. Neither the number of grafts nor type of grafts was associated with POAF. Furthermore, the rate of stroke was not associated with POAF.

摘要

背景

心房颤动(AF)和心房扑动是接受冠状动脉旁路移植术(CABG)的患者中最常见的两种心律失常类型,与发病率和死亡率增加有关。我们试图探讨术后心房颤动(POAF)患者旁路移植的类型和数量与心血管结局之间的关系。

假设

旁路移植的类型和数量与 POAF 相关。

方法

我们查询了 2002 年 1 月至 2007 年 7 月在 Baystate 医疗中心进行的 CABG 手术(包括和不包括瓣膜手术)的胸外科医师协会国家数据库。我们使用多变量逻辑回归模型来确定 POAF 的预测因素,并探讨 AF 在这个 CABG 后人群中对主要不良心脏结局的影响。

结果

共有 3068 名患者接受了 CABG 手术,其中 187 名(6.1%)接受了同期瓣膜置换或修复。POAF 的发生率为 38.3%。POAF 与 30 天内再入院显著相关(P<0.009),住院时间延长(P<<0.0001),30 天死亡率呈增加趋势(P=0.058)。POAF 与术后中风(P=0.92)、移植物类型(P=无统计学意义)或移植物数量(P=无统计学意义)之间无关联。

结论

如既往研究所示,患有 POAF 的患者经历了更高的发病率和死亡率。移植的数量和类型都与 POAF 无关。此外,中风的发生率与 POAF 无关。

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