Egloff N, Maecker F, Landmann G, von Känel R
Kompetenzbereich für Psychosomatische Medizin, Universitätsklinik für Allgemeine Innere Medizin, C.L. Lory-Haus, Inselspital Bern, 3010, Bern, Schweiz.
Schmerz. 2011 Dec;25(6):632-42. doi: 10.1007/s00482-011-1109-1.
Nondermatomal somatosensory deficits (NDSDs) are frequently found in chronic pain patients and allude to pain sensitization and pain centralization. In the clinical examination NDSDs are as a rule accompanied by hyposensitivity to touch and heat perception often with a quadrantal or hemibody distribution. The majority of NDSD patients show a trigger episode with a somatic nociceptive trauma in the case history. These somatic findings, however, never fully explain the pain disorder, analogue to the complex regional pain syndrome (CRPS). Most patients with chronic pain disorders as well as those with NDSD often report an antecedent period of high psychobiological stress. The data from functional imaging reveal a complex pattern of a central nervous dysregulation.
非皮节性躯体感觉障碍（NDSDs）在慢性疼痛患者中很常见，提示疼痛敏化和疼痛集中。在临床检查中，NDSDs通常伴有触觉和热觉减退，且常呈象限性或半侧身体分布。大多数NDSD患者在病史中有躯体伤害性创伤引发事件。然而，这些躯体检查结果从未完全解释疼痛障碍，这与复杂性区域疼痛综合征（CRPS）类似。大多数慢性疼痛障碍患者以及NDSD患者常报告有一段心理生物学高度应激的前期。功能成像数据显示出中枢神经调节异常的复杂模式。
