Momen Ali Akbar, Jelodar Gholamreza, Dehdashti Hamid
Department of Pediatric Neurology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, P.O. Box 173-61355, Ahvaz, Iran.
Int J Pediatr. 2011;2011:386984. doi: 10.1155/2011/386984. Epub 2011 Nov 2.
Background. Developmental disorders are failure or inability to acquire various age-specific skills at expected maturational age, which affects about 5-10% of preschool children. One of the most important methods for evaluation of developmentally delayed children is neuroimaging, especially, brain magnetic resonance imaging (MRI) that provides useful information regarding brain tissue structures and anomalies. Method and Material. In this study, hospital records of 580 developmentally delayed children (aged 2 months to 15 years) who admitted in pediatric ward of Golestan Hospital from 1997 to 2009 were selected. Information such as age, MRI findings were collected in the questionnaire and statistically analyzed. Results. Total, 580 children including 333 males (57.4%) and 247 females (42.6%) were studied. Abnormal brain MRI was observed in 340 (58.6%) cases (204 Males, 136 females). The finding includes nonspecific in 38 (6.6%), congenital and developmental anomalies of brain in 39 (6.7%), recognizable syndromes in 3 (0.5%), neurovascular diseases or trauma in 218 (37.6%), and metabolic or neurodegenerative diseases in 42 (7.2%) cases. Conclusion. Because 60% of all study groups showed abnormal brain MRI, using this method could be effective in diagnosis, management, and almost prognosis determination processes.
背景。发育障碍是指在预期的成熟年龄未能获得或无法获得各种特定年龄技能的情况,约5% - 10%的学龄前儿童受其影响。评估发育迟缓儿童最重要的方法之一是神经影像学检查,尤其是脑磁共振成像(MRI),它能提供有关脑组织结构和异常情况的有用信息。方法与材料。本研究选取了1997年至2009年在戈勒斯坦医院儿科病房收治的580名发育迟缓儿童(年龄2个月至15岁)的医院记录。在问卷中收集年龄、MRI检查结果等信息并进行统计分析。结果。总共研究了580名儿童,其中男性333名(57.4%),女性247名(42.6%)。340例(58.6%)(男性204例,女性136例)脑MRI检查结果异常。检查结果包括非特异性异常38例(6.6%)、脑先天性和发育性异常39例(6.7%)、可识别综合征3例(0.5%)、神经血管疾病或创伤218例(37.6%)以及代谢或神经退行性疾病42例(7.2%)。结论。由于所有研究组中有60%的儿童脑MRI检查结果异常,因此使用这种方法在诊断、管理以及几乎整个预后判定过程中可能是有效的。