Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.
Pediatrics. 2011 Dec;128(6):e1443-9. doi: 10.1542/peds.2011-1003. Epub 2011 Nov 28.
To describe (1) a cohort of children with paradoxical vocal-fold motion (PVFM) who were referred to a multidisciplinary airway center and (2) the outcomes of various treatment modalities including speech therapy, gastroesophageal reflux disease treatment, and psychiatric treatment.
This was a case series with chart review of children younger than 18 years with PVFM evaluated at a tertiary care pediatric airway center over a 36-month period.
Fifty-nine children with PVFM were evaluated. The cohort had a mean age of 13.64 years (range: 8-18 years) and a female-to-male ratio of 3:1. Speech therapy as an initial treatment resulted in a 63% (24 of 38) success rate after an average of 3.7 treatment sessions. Speech therapy was a more successful treatment than antireflux therapy (P = .001). Ten percent (6 of 59) of the children presented with a known psychiatric diagnosis, and 30% (18 of 59) of children in the cohort were ultimately diagnosed with a psychiatric condition. Children with inspiratory stridor at rest had a lower initial success rate with speech therapy (56%), a higher rate of underlying psychiatric disorders (75%), and a high rate of success after psychiatric treatment (100%) that required, on average, 3 sessions over a 2-month period.
To our knowledge, this is the largest study to date on pediatric PVFM. The majority of children with PVFM improve with speech therapy. Children with PVFM at rest may be better treated with psychiatric therapy than speech therapy. Furthermore, children who present with symptoms at rest may have a higher likelihood of underlying psychiatric disease.
描述(1)一组被转介到多学科气道中心的具有矛盾性声带运动(PVFM)的儿童,以及(2)各种治疗方式的结果,包括言语治疗、胃食管反流病治疗和精神科治疗。
这是一项病例系列研究,对在 36 个月内于三级儿科气道中心接受评估的年龄小于 18 岁的 PVFM 儿童进行了图表回顾。
共评估了 59 例 PVFM 患儿。该队列的平均年龄为 13.64 岁(范围:8-18 岁),男女比例为 3:1。言语治疗作为初始治疗,在平均 3.7 次治疗后,成功率为 63%(24/38)。言语治疗的成功率高于抗反流治疗(P=0.001)。10%(6/59)的儿童有已知的精神科诊断,30%(59 例中的 18 例)的患儿最终被诊断为精神疾病。在休息时出现吸气性喘鸣的儿童,言语治疗的初始成功率较低(56%),潜在精神障碍的发生率较高(75%),且精神科治疗后的成功率较高(100%),平均需要 3 次治疗,持续 2 个月。
据我们所知,这是迄今为止关于儿科 PVFM 的最大研究。大多数 PVFM 患儿可通过言语治疗改善。休息时出现 PVFM 的儿童可能更适合接受精神科治疗,而非言语治疗。此外,在休息时出现症状的儿童更有可能患有潜在的精神疾病。