关于甲砜霉素和氯霉素对家兔骨髓细胞体内及体外核酸与蛋白质合成的影响
On the effects of thiamphenicol and chloramphenicol on nucleic acid and protein synthesis in rabbit bone marrow cells in vivo and in vitro.
作者信息
Nijhof W, Wierenga P K
出版信息
Experientia. 1979 May 15;35(5):686-8. doi: 10.1007/BF01960400.
PMID:221239
Abstract
Besides the in vivo effects of thiamphenicol (TAP), this study shows the in vitro effects of TAP and D- and L-threo-chloramphenicol (CAP) on the synthesis of DNA, RNA, protein and hemoglobin in marrow cells and reticulocytes. The experiments make it likely that TAP exerts its action on a stem cell in a proliferating phase.
摘要
除了甲砜霉素（TAP）的体内效应外，本研究还展示了TAP以及D-和L-苏式氯霉素（CAP）对骨髓细胞和网织红细胞中DNA、RNA、蛋白质及血红蛋白合成的体外效应。这些实验表明，TAP可能对处于增殖期的干细胞发挥作用。
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