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Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of end points in noninsulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial.

作者信息

Dhaun Neeraj, Webb David J

出版信息

Hypertension. 2012 Jan;59(1):e1. doi: 10.1161/HYPERTENSIONAHA.111.186064. Epub 2011 Nov 28.

DOI:10.1161/HYPERTENSIONAHA.111.186064
PMID:22124433
Abstract
摘要

相似文献

1
Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of end points in noninsulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial.氯沙坦治疗期间尿酸降低对肾脏结局的影响：对非胰岛素依赖型糖尿病血管紧张素II拮抗剂氯沙坦试验终点降低的事后分析。
Hypertension. 2012 Jan;59(1):e1. doi: 10.1161/HYPERTENSIONAHA.111.186064. Epub 2011 Nov 28.
2
Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of endpoints in non-insulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial.氯沙坦治疗中降低尿酸对肾脏结局的影响：非胰岛素依赖型糖尿病终点降低的血管紧张素Ⅱ拮抗剂氯沙坦试验的事后分析。
Hypertension. 2011 Jul;58(1):2-7. doi: 10.1161/HYPERTENSIONAHA.111.171488. Epub 2011 May 31.
3
Pre-renal success.肾前性成功。
Kidney Int. 2012 Mar;81(6):596; author reply 597. doi: 10.1038/ki.2011.418.
4
Have we observed the implications of the acute fall in eGFR during treatment with losartan?我们是否观察到了氯沙坦治疗期间估算肾小球滤过率（eGFR）急剧下降的影响？
Kidney Int. 2012 Mar;81(6):595-6; author reply 597. doi: 10.1038/ki.2011.419.
5
An acute fall in estimated glomerular filtration rate during treatment with losartan predicts a slower decrease in long-term renal function.在使用氯沙坦治疗期间估计肾小球滤过率的急剧下降预示着长期肾功能下降速度较慢。
Kidney Int. 2011 Aug;80(3):282-7. doi: 10.1038/ki.2011.79. Epub 2011 Mar 30.
6
Estimated GFR decline as a surrogate end point for kidney failure: a post hoc analysis from the Reduction of End Points in Non-Insulin-Dependent Diabetes With the Angiotensin II Antagonist Losartan (RENAAL) study and Irbesartan Diabetic Nephropathy Trial (IDNT).估算肾小球滤过率下降作为肾衰竭的替代终点：来自非胰岛素依赖型糖尿病患者应用血管紧张素Ⅱ拮抗剂氯沙坦减少终点事件（RENAAL）研究和厄贝沙坦糖尿病肾病试验（IDNT）的事后分析。
Am J Kidney Dis. 2014 Feb;63(2):244-50. doi: 10.1053/j.ajkd.2013.09.016. Epub 2013 Nov 6.
7
The therapeutic tradeoff between the adverse impacts of a lower GFR and long-term renal protection.较低肾小球滤过率（GFR）的不良影响与长期肾脏保护之间的治疗权衡。
Kidney Int. 2012 Feb;81(3):323-4. doi: 10.1038/ki.2011.378.
8
Acute fall in glomerular filtration rate with renin-angiotensin system inhibition: a biomeasure of therapeutic success?肾素-血管紧张素系统抑制导致肾小球滤过率急剧下降：治疗成功的生物标志物？
Kidney Int. 2011 Aug;80(3):235-7. doi: 10.1038/ki.2011.132.
9
Long-term comparison of losartan and enalapril on kidney function in hypertensive type 2 diabetics with early nephropathy.氯沙坦与依那普利对伴早期肾病的高血压2型糖尿病患者肾功能的长期比较
Kidney Int. 2000 Aug;58(2):762-9. doi: 10.1046/j.1523-1755.2000.00224.x.
10
Beneficial effect of switching from a combination of angiotensin II receptor blockers other than losartan and thiazides to a fixed dose of losartan/hydrochlorothiazide on uric acid metabolism in hypertensive patients.将血管紧张素 II 受体阻滞剂（除氯沙坦以外）与噻嗪类利尿剂的联合用药转换为固定剂量的氯沙坦/氢氯噻嗪对高血压患者尿酸代谢的有益影响。
Clin Exp Hypertens. 2011;33(8):565-70. doi: 10.3109/10641963.2011.577487. Epub 2011 Sep 29.

引用本文的文献

1
Uric acid lowering for slowing CKD progression after the CKD-FIX trial: a solved question or still a dilemma?CKD-FIX试验后降低尿酸以减缓慢性肾脏病进展：是已解决的问题还是仍存的困境？
Clin Kidney J. 2022 Mar 12;15(9):1666-1674. doi: 10.1093/ckj/sfac075. eCollection 2022 Sep.
2
Spironolactone increases serum uric acid levels in patients with chronic kidney disease.螺内酯可升高慢性肾脏病患者的血清尿酸水平。
J Hum Hypertens. 2014 Mar;28(3):210-1. doi: 10.1038/jhh.2013.66. Epub 2013 Jul 18.