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肝切除术后发病率和死亡率的评估。

Assessment of morbidity and mortality after hepatic resections.

作者信息

Resende Vivian, Rezende-Neto João Batista de, Fernandes Juliana Santana, Cunha-Melo José Renan da

机构信息

Department of Surgery, Universidade Federal de Minas Gerais, MG-BR.

出版信息

Rev Col Bras Cir. 2011 Sep-Oct;38(5):323-6.

PMID:22124643
Abstract

OBJECTIVE

To describe morbidity and mortality in patients undergoing hepatectomy.

METHODS

We evaluated hepatectomy according to type of surgery, perioperative blood transfusion, hospital stay, complications and postoperative mortality. For statistical analysis we used the Ficher's exact test, considering significant p values <0.05.

RESULTS

We performed 22 (31.43%) major hepatectomies, 13 (18.57%) being right hepatectomies extended to segments IVa and IVb, nine (12.86%) left hepatectomies, among these, six included the segment I. We conducted 48 (68.57%) minor hepatectomies, 36 (51.43%) segmental resections and 12 (17.14%) non-anatomical resections. The main indication for resection was colorectal adenocarcinoma metastasis in 27 (38.57%) patients. The higher incidence of primary tumor was hepatocellular carcinoma in 14 (20%) patients, followed by cholangiocarcinoma in six (8.57%). Among the 13 (18.57%) resections for benign diseases, the predominant one was intrahepatic lithiasis (n = 6). Six patients (8.57%) received perioperative blood transfusion. Hospital stay ranged from 2 to 28 days (mean four days). Eight (11.43%) patients developed postoperative complications. Overall mortality was 8.57%, mostly in patients with hepatocellular carcinoma (5.71%).

CONCLUSION

Metastatic colorectal adenocarcinoma was the main indication for surgery and minor hepatectomies were the most common procedures. Despite the low overall incidence of postoperative complications, there was high morbidity and mortality in cirrhotic patients with hepatocellular carcinoma.

摘要

目的

描述接受肝切除术患者的发病率和死亡率。

方法

我们根据手术类型、围手术期输血情况、住院时间、并发症及术后死亡率对肝切除术进行评估。统计分析采用Fisher精确检验,p值<0.05为有统计学意义。

结果

我们实施了22例(31.43%)大肝切除术,其中13例(18.57%)为延伸至IVa和IVb段的右肝切除术,9例(12.86%)为左肝切除术,其中6例包括I段。我们实施了48例(68.57%)小肝切除术,36例(51.43%)为节段性切除术,12例(17.14%)为非解剖性切除术。主要切除指征是27例(38.57%)患者发生结直肠癌转移。原发肿瘤发病率较高的是14例(20%)肝细胞癌患者,其次是6例(8.57%)胆管癌患者。在13例(18.57%)因良性疾病进行的切除术中,最主要的是肝内结石(n = 6)。6例(8.57%)患者接受了围手术期输血。住院时间为2至28天(平均4天)。8例(11.43%)患者出现术后并发症。总体死亡率为8.57%,主要发生在肝细胞癌患者中(5.71%)。

结论

转移性结直肠癌是手术的主要指征,小肝切除术是最常见的手术方式。尽管术后并发症的总体发生率较低,但肝细胞癌肝硬化患者的发病率和死亡率较高。

相似文献

1
Assessment of morbidity and mortality after hepatic resections.肝切除术后发病率和死亡率的评估。
Rev Col Bras Cir. 2011 Sep-Oct;38(5):323-6.
2
Getting started as a hepatobiliary surgeon: lessons learned from the first 100 hepatectomies as a consultant.成为一名肝胆外科医生的起步:作为顾问医生完成首例100例肝切除术后的经验教训。
N Z Med J. 2005 Feb 25;118(1210):U1322.
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Improvement in perioperative outcome after hepatic resection: analysis of 1,803 consecutive cases over the past decade.肝切除术后围手术期结局的改善:对过去十年中1803例连续病例的分析
Ann Surg. 2002 Oct;236(4):397-406; discussion 406-7. doi: 10.1097/01.SLA.0000029003.66466.B3.
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Operative risks of major hepatic resections.肝大部切除术的手术风险。
Hepatogastroenterology. 1998 Jan-Feb;45(19):184-90.
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Is radical hepatic surgery safe?根治性肝脏手术安全吗?
Am J Surg. 1998 Feb;175(2):161-3. doi: 10.1016/S0002-9610(97)00265-1.
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One hundred consecutive hepatobiliary resections for biliary hilar malignancy: preoperative blood donation, blood loss, transfusion, and outcome.连续100例肝门部胆管恶性肿瘤的肝切除手术:术前自体输血、失血情况、输血情况及手术结果
Surgery. 2005 Feb;137(2):148-55. doi: 10.1016/j.surg.2004.06.006.
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The extent of resection influences outcome following hepatectomy for colorectal liver metastases.切除范围影响结直肠癌肝转移肝切除术后的预后。
Eur J Surg Oncol. 2004 May;30(4):370-6. doi: 10.1016/j.ejso.2004.01.011.
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Left hepatic trisectionectomy for hepatobiliary malignancies.用于肝胆恶性肿瘤的左肝三叶切除术
J Am Coll Surg. 2006 Sep;203(3):311-21. doi: 10.1016/j.jamcollsurg.2006.05.290. Epub 2006 Jul 13.
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Risk factors for perioperative morbidity and mortality after extended hepatectomy for hepatocellular carcinoma.肝细胞癌扩大肝切除术后围手术期发病和死亡的危险因素。
Br J Surg. 2003 Jan;90(1):33-41. doi: 10.1002/bjs.4018.
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Impact of age on the outcome of liver resections.年龄对肝切除手术结果的影响。
Am Surg. 2004 May;70(5):453-60.

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