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[精神病学的变色龙——神经梅毒的精神症状表现]

[The chameleon of psychiatry - psychiatric manifestations of neurosyphilis].

作者信息

Friedrich Fabian, Geusau Alexandra, Friedrich Michaela-Elena, Vyssoki Benjamin, Pfleger Tibor, Aigner Martin

机构信息

Universitätsklinik für Psychiatrie und Psychotherapie, Abteilung für Sozialpsychiatrie, Medizinische Universität Wien, Österreich.

出版信息

Psychiatr Prax. 2012 Jan;39(1):7-13. doi: 10.1055/s-0031-1276935. Epub 2011 Nov 28.

Abstract

OBJECTIVE

Recent epidemiological data have shown a significant increase in the prevalence of syphilis. If left untreated, up to 30 % of patients may develop tertiary syphilis, which can manifest as neurosyphilis. The aim of our review is to evaluate psychiatric manifestations of neurosyphilis according to ICD-10.

METHODS

A systematic electronic search for published studies (1995-2010) was performed using the databases Medline, Embase, Cochrane as well as the search engines Scopus and Google Scholar.

RESULTS

113 studies were used for detailed analysis. Clinical manifestations of various forms of neurosyphilis are protean, numerous and non-specific and could be on the differential diagnosis for many psychiatric presentations according to ICD-10.

CONCLUSION

Due to our results, the difficulties in diagnosing syphilis and current epidemiological data, routine screening tests are still mandatory in the psychiatric field. Further, neurosyphilis still has to be considered in the differential diagnosis within the context of psychiatric conditions and diseases.

摘要

目的

近期流行病学数据显示梅毒患病率显著上升。若不治疗,高达30%的患者可能发展为三期梅毒,可表现为神经梅毒。我们综述的目的是根据国际疾病分类第十版(ICD - 10)评估神经梅毒的精神症状。

方法

使用Medline、Embase、Cochrane数据库以及Scopus和谷歌学术搜索引擎,对已发表的研究(1995 - 2010年)进行系统的电子检索。

结果

113项研究用于详细分析。根据ICD - 10,各种形式神经梅毒的临床表现多样、繁多且不具特异性,可能是许多精神疾病表现的鉴别诊断依据。

结论

基于我们的研究结果、梅毒诊断的困难以及当前的流行病学数据,精神科领域仍必须进行常规筛查测试。此外,在精神疾病的鉴别诊断中仍需考虑神经梅毒。

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