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香烟烟雾可激活鸟苷酸环化酶并增加组织中3',5'-环磷酸鸟苷的含量。

Cigarette smoke activates guanylate cyclase and increases guanosine 3',5'-monophosphate in tissues.

作者信息

Arnold W P, Aldred R, Murad F

出版信息

Science. 1977 Dec 2;198(4320):934-6. doi: 10.1126/science.22126.

DOI:10.1126/science.22126
PMID:22126
Abstract

The gaseous phase of cigarette smoke induced a 2- to 36-fold increase in the activity of guanylate cyclase in supernatant and particulate fractions from various rat and bovine tissues over basal activity. The characteristics of this phenomenon paralleled those of the activation of guanylate cyclase by nitric oxide, which is a component of tobacco smoke.

摘要

香烟烟雾的气相成分使来自各种大鼠和牛组织的上清液和微粒部分中的鸟苷酸环化酶活性比基础活性增加了2至36倍。这种现象的特征与一氧化氮(烟草烟雾的一种成分)激活鸟苷酸环化酶的特征相似。

相似文献

1
Cigarette smoke activates guanylate cyclase and increases guanosine 3',5'-monophosphate in tissues.香烟烟雾可激活鸟苷酸环化酶并增加组织中3',5'-环磷酸鸟苷的含量。
Science. 1977 Dec 2;198(4320):934-6. doi: 10.1126/science.22126.
2
Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations.一氧化氮可激活鸟苷酸环化酶,并提高各种组织制剂中鸟苷 3':5'-环磷酸水平。
Proc Natl Acad Sci U S A. 1977 Aug;74(8):3203-7. doi: 10.1073/pnas.74.8.3203.
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Inhaled nitric oxide decreases pulmonary soluble guanylate cyclase protein levels in 1-month-old lambs.吸入一氧化氮可降低1月龄羔羊肺组织中可溶性鸟苷酸环化酶蛋白水平。
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Atrial natriuretic factor and sodium nitroprusside increase cyclic GMP in cultured rat lung fibroblasts by activating different forms of guanylate cyclase.心房利钠因子和硝普钠通过激活不同形式的鸟苷酸环化酶增加培养的大鼠肺成纤维细胞中的环磷酸鸟苷。
Biochem J. 1987 May 15;244(1):69-74. doi: 10.1042/bj2440069.
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Requirement for heme in the activation of purified guanylate cyclase by nitric oxide.一氧化氮激活纯化的鸟苷酸环化酶时对血红素的需求。
Biochim Biophys Acta. 1983 Jun 29;745(3):310-21. doi: 10.1016/0167-4838(83)90063-8.
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Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine.硝普钠、硝酸甘油和一氧化氮对各种组织制剂中鸟苷酸环化酶的刺激作用以及与叠氮化钠和羟胺作用的比较。
J Cyclic Nucleotide Res. 1977 Feb;3(1):23-35.
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Activation of guanylate cyclase and the regulatory role of cyclic 3',5'-guanosine monophosphate.
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Alterations in the subcellular distribution of Guanylate cyclase and its responsiveness to nitric oxide in diethylstilbestrol-induced renal tumors.己烯雌酚诱导的肾肿瘤中鸟苷酸环化酶亚细胞分布的改变及其对一氧化氮的反应性
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Properties of purified soluble guanylate cyclase activated by nitric oxide and sodium nitroprusside.一氧化氮和硝普钠激活的纯化可溶性鸟苷酸环化酶的特性
J Cyclic Nucleotide Res. 1982;8(1):17-25.
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Comparative effects of activation of soluble and particulate guanylyl cyclase on cyclic GMP elevation and relaxation of bovine tracheal smooth muscle.可溶性和颗粒性鸟苷酸环化酶激活对牛气管平滑肌中环鸟苷酸升高及舒张的比较效应。
Br J Pharmacol. 1995 Jul;115(5):723-32. doi: 10.1111/j.1476-5381.1995.tb14993.x.

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