Gillespie W J
University of Newcastle, New South Wales, Australia.
Infect Dis Clin North Am. 1990 Sep;4(3):465-84.
Although a small number of infections in total joint replacements are blood borne from distant sources, most infections appear to have been derived at operation. Strenuous attempts to reduce this risk by cleaning the air in the wound environment, coupled with prophylactic antibiotics, have reduced infection rates by an order of magnitude in a decade. During that time the potential for exchange arthroplasty in established infection has been shown, and the results are encouraging. Rigorous infection control is the key to containing this difficult and expensive problem.
虽然全关节置换术中的少数感染是由远处血行传播而来，但大多数感染似乎是在手术时发生的。通过清洁伤口环境中的空气以及使用预防性抗生素来大力降低这种风险的尝试，已在十年内将感染率降低了一个数量级。在此期间，已证明在已发生感染的情况下进行关节置换术的可能性，且结果令人鼓舞。严格的感染控制是遏制这个棘手且昂贵问题的关键。
