• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

机架旋转时间对计划质量和剂量验证的影响——容积旋转调强弧形治疗(VMAT)与强度调制放疗(IMRT)。

Impact of gantry rotation time on plan quality and dosimetric verification--volumetric modulated arc therapy (VMAT) vs. intensity modulated radiotherapy (IMRT).

机构信息

Gemeinschaftspraxis für Strahlentherapie Singen-Friedrichshafen, Friedrichshafen, Germany.

出版信息

Strahlenther Onkol. 2011 Dec;187(12):812-9. doi: 10.1007/s00066-011-2263-1. Epub 2011 Nov 29.

DOI:10.1007/s00066-011-2263-1
PMID:22127360
Abstract

BACKGROUND AND PURPOSE

To compare plan quality criteria and dosimetric accuracy of step-and-shoot intensity-modulated radiotherapy (ss-IMRT) and volumetric modulated arc radiotherapy (VMAT) using two different gantry rotation times.

PATIENTS AND METHODS

This retrospective planning study based on 20 patients was comprised of 10 prostate cancer (PC) and 10 head and neck (HN) cancer cases. Each plan contained two target volumes: a primary planning target volume (PTV) and a boost volume. For each patient, one ss-IMRT plan and two VMAT plans at 90 s (VMAT90) and 120 s (VMAT120) per arc were generated with the Pinnacle© planning system. Two arcs were provided for the PTV plans and a single arc for boost volumes. Dosimetric verification of the plans was performed using a 2D ionization chamber array placed in a full scatter phantom.

RESULTS

VMAT reduced delivery time and monitor units for both treatment sites compared to IMRT. VMAT120 vs. VMAT90 increased delivery time and monitor units in PC plans without improving plan quality. For HN cases, VMAT120 provided comparable organs at risk sparing and better target coverage and conformity than VMAT90. In the VMAT plan verification, an average of 97.1% of the detector points passed the 3 mm, 3% γ criterion, while in IMRT verification it was 98.8%.

CONCLUSION

VMAT90, VMAT120, and IMRT achieved comparable treatment plans. Slower gantry movement in VMAT120 plans only improves dosimetric quality for highly complex targets.

摘要

背景与目的

比较两种不同机架旋转时间的步进式强度调制放射治疗(ss-IMRT)和容积旋转调强放疗(VMAT)的计划质量标准和剂量学准确性。

患者与方法

这项回顾性计划研究基于 20 名患者,包括 10 例前列腺癌(PC)和 10 例头颈部(HN)癌症病例。每个计划包含两个靶区:一个主要计划靶区(PTV)和一个加量靶区。对于每个患者,使用 Pinnacle© 计划系统生成一个 ss-IMRT 计划和两个 VMAT 计划,即 90 秒(VMAT90)和 120 秒(VMAT120)每弧。PTV 计划提供两个弧,加量靶区提供一个弧。使用放置在全散射体模中的二维电离室阵列对计划进行剂量验证。

结果

与 IMRT 相比,VMAT 降低了两个治疗部位的治疗时间和监测单位。与 VMAT90 相比,VMAT120 增加了 PC 计划的治疗时间和监测单位,但并未改善计划质量。对于 HN 病例,VMAT120 提供了可比的危及器官保护和更好的靶区覆盖和适形度,优于 VMAT90。在 VMAT 计划验证中,平均有 97.1%的探测器点通过了 3mm、3%γ标准,而在 IMRT 验证中为 98.8%。

结论

VMAT90、VMAT120 和 IMRT 实现了可比的治疗计划。VMAT120 计划中较慢的机架运动仅能改善高度复杂靶区的剂量学质量。

相似文献

1
Impact of gantry rotation time on plan quality and dosimetric verification--volumetric modulated arc therapy (VMAT) vs. intensity modulated radiotherapy (IMRT).机架旋转时间对计划质量和剂量验证的影响——容积旋转调强弧形治疗(VMAT)与强度调制放疗(IMRT)。
Strahlenther Onkol. 2011 Dec;187(12):812-9. doi: 10.1007/s00066-011-2263-1. Epub 2011 Nov 29.
2
Effect of photon-beam energy on VMAT and IMRT treatment plan quality and dosimetric accuracy for advanced prostate cancer.光子束能量对前列腺癌调强适形放疗和容积旋转调强放疗计划质量和剂量学准确性的影响。
Strahlenther Onkol. 2011 Dec;187(12):792-8. doi: 10.1007/s00066-011-1150-0. Epub 2011 Nov 29.
3
Volumetric-modulated arc therapy vs. c-IMRT in esophageal cancer: a treatment planning comparison.容积旋转调强弧形治疗与常规调强适形放疗在食管癌中的比较:一项治疗计划的比较。
World J Gastroenterol. 2012 Oct 7;18(37):5266-75. doi: 10.3748/wjg.v18.i37.5266.
4
Volumetric-modulated arc therapy versus intensity-modulated radiotherapy for large volume retroperitoneal sarcomas: A comparative analysis of dosimetric and treatment delivery parameters.容积调强弧形放疗与调强放疗治疗大体积腹膜后肉瘤的剂量学和治疗实施参数比较分析
J Appl Clin Med Phys. 2018 Jan;19(1):276-281. doi: 10.1002/acm2.12230. Epub 2017 Nov 27.
5
Dosimetric comparison of MR-linac-based IMRT and conventional VMAT treatment plans for prostate cancer.基于磁共振直线加速器的调强放射治疗(IMRT)与传统容积调强弧形治疗(VMAT)前列腺癌治疗计划的剂量学比较。
Radiat Oncol. 2021 Jul 21;16(1):133. doi: 10.1186/s13014-021-01858-7.
6
Treatment plan quality and delivery accuracy assessments on 3 IMRT delivery methods of stereotactic body radiotherapy for spine tumors.脊柱肿瘤立体定向体部放射治疗三种调强放射治疗(IMRT) delivery方法的治疗计划质量和交付准确性评估。 (备注:原文中“delivery”此处似有拼写错误,推测可能是“IMRT”,但按要求准确翻译此句如此)
Med Dosim. 2019;44(1):11-14. doi: 10.1016/j.meddos.2017.12.009. Epub 2018 Feb 21.
7
Assessing the role of volumetric modulated arc therapy (VMAT) relative to IMRT and helical tomotherapy in the management of localized, locally advanced, and post-operative prostate cancer.评估容积旋转调强放疗(VMAT)相对于调强放疗(IMRT)和螺旋断层放疗(Tomo)在局限性、局部晚期和术后前列腺癌治疗中的作用。
Int J Radiat Oncol Biol Phys. 2011 Aug 1;80(5):1550-8. doi: 10.1016/j.ijrobp.2010.10.024. Epub 2011 May 3.
8
A dosimetric comparison of volumetric modulated arc therapy (VMAT) and non-coplanar intensity modulated radiotherapy (IMRT) for nasal cavity and paranasal sinus cancer.容积调强弧形放疗(VMAT)与非共面调强放疗(IMRT)治疗鼻腔和鼻窦癌的剂量学比较
Radiat Oncol. 2014 Aug 30;9:193. doi: 10.1186/1748-717X-9-193.
9
Dosimetric comparison of hybrid volumetric-modulated arc therapy, volumetric-modulated arc therapy, and intensity-modulated radiation therapy for left-sided early breast cancer.左侧早期乳腺癌的混合容积调强弧形放疗、容积调强弧形放疗和调强放射治疗的剂量学比较
Med Dosim. 2015 Autumn;40(3):262-7. doi: 10.1016/j.meddos.2015.05.003. Epub 2015 Jun 23.
10
Assessing the feasibility of volumetric-modulated arc therapy using simultaneous integrated boost (SIB-VMAT): An analysis for complex head-neck, high-risk prostate and rectal cancer cases.评估使用同步整合加量的容积调强弧形放疗(SIB-VMAT)的可行性:针对复杂头颈癌、高危前列腺癌和直肠癌病例的分析。
Med Dosim. 2014 Spring;39(1):108-16. doi: 10.1016/j.meddos.2013.11.001. Epub 2013 Dec 15.

引用本文的文献

1
Dosimetric accuracy of low dose rate volumetric modulated arc therapy delivery in an Elekta Versa HD linear accelerator for pulsed low dose rate treatment of recurrent high-grade glioma using Monaco planning system: Low dose rate VMAT-based PLDR in Elekta Linac.在Elekta Versa HD直线加速器中,使用Monaco治疗计划系统进行低剂量率容积调强弧形放疗以对复发性高级别胶质瘤进行脉冲式低剂量率治疗的剂量学准确性:Elekta直线加速器中基于低剂量率容积调强弧形放疗的脉冲式低剂量率治疗
J Appl Clin Med Phys. 2025 Sep;26(9):e70253. doi: 10.1002/acm2.70253.
2
Effect of isocenter deviation on volume modulated arc therapy plan results and gamma passing rate in the treatment of cervical cancer.等中心偏差对宫颈癌容积调强弧形放疗计划结果及伽马通过率的影响
Transl Cancer Res. 2021 Oct;10(10):4403-4412. doi: 10.21037/tcr-21-1514.
3

本文引用的文献

1
Volumetric modulated arc therapy for advanced pancreatic cancer.容积调强弧形治疗技术治疗晚期胰腺癌。
Strahlenther Onkol. 2010 Jul;186(7):382-7. doi: 10.1007/s00066-010-2094-5. Epub 2010 Jun 24.
2
Clinical implementation of volumetric intensity-modulated arc therapy (VMAT) with ERGO++.容积调强弧形治疗(VMAT)的 ERGO++临床应用。
Strahlenther Onkol. 2010 May;186(5):280-8. doi: 10.1007/s00066-010-2071-z. Epub 2010 Apr 26.
3
Single Arc Volumetric Modulated Arc Therapy of head and neck cancer.头颈部癌症的单次弧形容积调强弧形治疗。
Evaluation of a new foetal shielding device for pregnant brain tumour patients.评估一种新的用于孕妇脑瘤患者的胎儿屏蔽装置。
Radiat Oncol. 2021 Jun 13;16(1):109. doi: 10.1186/s13014-021-01836-z.
4
Dosimetric effect of limited aperture multileaf collimator on VMAT plan quality: A study of prostate and head-and-neck cancers.有限孔径多叶准直器对容积调强放疗计划质量的剂量学影响:前列腺癌和头颈癌的研究
Rep Pract Oncol Radiother. 2018 May-Jun;23(3):189-198. doi: 10.1016/j.rpor.2018.02.006. Epub 2018 Mar 21.
5
Validation of the relative insensitivity of volumetric-modulated arc therapy (VMAT) plan quality to gantry space resolution.容积调强弧形治疗(VMAT)计划质量对机架空间分辨率相对不敏感的验证。
J Radiat Res. 2017 Jul 1;58(4):579-590. doi: 10.1093/jrr/rrw114.
6
Estimation of second cancer risk after radiotherapy for rectal cancer: comparison of 3D conformal radiotherapy and volumetric modulated arc therapy using different high dose fractionation schemes.直肠癌放疗后第二原发癌风险的评估:使用不同高剂量分割方案的三维适形放疗与容积调强弧形放疗的比较
Radiat Oncol. 2016 Nov 10;11(1):149. doi: 10.1186/s13014-016-0723-6.
7
Patient-related quality assurance with different combinations of treatment planning systems, techniques, and machines : A multi-institutional survey.不同治疗计划系统、技术和机器组合下的患者相关质量保证:一项多机构调查。
Strahlenther Onkol. 2017 Jan;193(1):46-54. doi: 10.1007/s00066-016-1064-y. Epub 2016 Nov 3.
8
mARC vs. IMRT radiotherapy of the prostate with flat and flattening-filter-free beam energies.使用扁平和平坦滤过器自由束能量对前列腺进行mARC与调强放射治疗的比较。
Radiat Oncol. 2014 Nov 26;9:250. doi: 10.1186/s13014-014-0250-2.
9
Influence of metallic dental implants and metal artefacts on dose calculation accuracy.金属牙科植入物和金属伪影对剂量计算准确性的影响。
Strahlenther Onkol. 2015 Mar;191(3):234-41. doi: 10.1007/s00066-014-0774-2. Epub 2014 Oct 31.
10
Clinical and dosimetric evaluation of RapidArc versus standard sliding window IMRT in the treatment of head and neck cancer.快速弧形调强放疗与标准滑动窗口调强放疗治疗头颈癌的临床与剂量学评估
Strahlenther Onkol. 2015 Jan;191(1):43-50. doi: 10.1007/s00066-014-0742-x. Epub 2014 Aug 29.
Radiother Oncol. 2010 May;95(2):142-8. doi: 10.1016/j.radonc.2010.01.011. Epub 2010 Feb 24.
4
Intensity-modulated arc therapy with simultaneous integrated boost in the treatment of primary irresectable cervical cancer. Treatment planning, quality control, and clinical implementation.调强弧形放疗联合同步整合加量在原发性不可切除宫颈癌治疗中的应用。治疗计划、质量控制及临床实施。
Strahlenther Onkol. 2009 Dec;185(12):799-807. doi: 10.1007/s00066-009-1986-8.
5
Volumetric modulated arc therapy (VMAT) vs. serial tomotherapy, step-and-shoot IMRT and 3D-conformal RT for treatment of prostate cancer.容积旋转调强弧形治疗(VMAT)与序贯断层调强放疗、静态调强放疗和三维适形放疗治疗前列腺癌的比较。
Radiother Oncol. 2009 Nov;93(2):226-33. doi: 10.1016/j.radonc.2009.08.011. Epub 2009 Sep 16.
6
Is a single arc sufficient in volumetric-modulated arc therapy (VMAT) for complex-shaped target volumes?对于复杂形状的靶区容积调强弧形治疗(VMAT),单弧是否足够?
Radiother Oncol. 2009 Nov;93(2):259-65. doi: 10.1016/j.radonc.2009.08.015. Epub 2009 Sep 10.
7
Development and evaluation of an efficient approach to volumetric arc therapy planning.容积弧形调强放疗计划的高效方法的开发与评估。
Med Phys. 2009 Jun;36(6):2328-39. doi: 10.1118/1.3132234.
8
A comparison of volumetric modulated arc therapy and conventional intensity-modulated radiotherapy for frontal and temporal high-grade gliomas.容积旋转调强弧形治疗与常规强度调制放射治疗在前额和颞叶高级别胶质瘤中的比较。
Int J Radiat Oncol Biol Phys. 2010 Mar 15;76(4):1177-84. doi: 10.1016/j.ijrobp.2009.03.013. Epub 2009 Jun 27.
9
Volumetric modulated arc therapy: planning and evaluation for prostate cancer cases.容积调强弧形治疗:前列腺癌病例的计划和评估。
Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1456-62. doi: 10.1016/j.ijrobp.2009.03.033. Epub 2009 Jun 18.
10
Development of RTOG consensus guidelines for the definition of the clinical target volume for postoperative conformal radiation therapy for prostate cancer.制定 RTOG 共识指南,以定义前列腺癌术后适形放射治疗的临床靶区。
Int J Radiat Oncol Biol Phys. 2010 Feb 1;76(2):361-8. doi: 10.1016/j.ijrobp.2009.02.006. Epub 2009 Apr 23.