Sekino Y, Hata M, Endo M, Tabayashi K, Suzuki Y, Mohri H
Department of Thoracic and Cardiovascular Surgery, Tohoku University School of Medicine, Sendai, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1990 Jul;38(7):1183-7.
A 38-year-old man was admitted to our hospital with complaints of palpitation and shortness of breath. On auscultation, presence of severe aortic regurgitation was found. Seven years prior to admission, he had undergone rectal polypectomy complicated by postoperative serious hemorrhage which had led to the diagnosis of von Willebrand's disease. Aortic valve replacement with a Björk-Shiley prosthesis was performed under routine cardio-pulmonary bypass. He received Confact-F as a replacement therapy of factor VIII throughout the perioperative period. His operative and postoperative courses were uneventful without difficulties in hemostasis. The patient was placed on a regimen of anticoagulation (Warfarin sodium) without increase in the bleeding tendency. He is asymptomatic and doing well six months after the operation.
一名38岁男性因心悸和呼吸急促入院。听诊发现有严重主动脉瓣反流。入院前七年，他接受了直肠息肉切除术，术后并发严重出血，导致诊断为血管性血友病。在常规体外循环下进行了带 Björk-Shiley 人工瓣膜的主动脉瓣置换术。围手术期他接受了康法克F作为 VIII 因子替代疗法。他的手术和术后过程顺利，止血无困难。患者接受抗凝治疗（华法林钠），出血倾向未增加。术后六个月他无症状，情况良好。
