Suppr超能文献

神经调节治疗慢性疼痛的效果。

Results of neuromodulation for the management of chronic pain.

机构信息

Department of Neurosurgery, 10th Militray Clinical Hospital, Bydgoszcz, Poland.

出版信息

Neurol Neurochir Pol. 2011 Sep-Oct;45(5):445-51. doi: 10.1016/s0028-3843(14)60312-1.

Abstract

Background and purpose : Neuromodulative treatment of chronic pain syndromes is a modern mode of treatment of neuropathic and ischaemic pain. Its effectiveness is well documented in the literature. The objective of this work is to present the results of treatment of chronic pain syndromes on the basis of eight-year experience in our department. Material and methods : Since 2002, we have conducted 9 operations of motor cortex stimulation (MCS), 2 of deep brain stimulation (DBS), 45 of spinal cord stimulation (SCS) and 5 of sacral root stimulation (SRS) in the treatment of chronic pain. Results : We obtained good long-term results of neuromodulation in the form of clinical improvement (> 50%) in 4 of 9 patients with MCS (44%), in 13 diagnosed with failed back surgery syndrome (FBSS), 8 with other neuropathic pain, and 11 with angina pectoris from a group of 45 treated with SCS. Sacral root stimulation has been successful in 3 of 5 patients with perianal pain. The best treatment results in SCS, although not statistically significant, were observed in patients treated due to FBSS (13 out of 15) and angina pectoris (11 out of 15) (p = 0.12). In patients with neuropathic pain, peripheral and central, improvement was obtained in 8 out of 15 patients. Conclusions : A good indication for spinal cord stimulation is FBSS and angina pectoris. Motor cortex stimulation is helpful in the treatment of chronic central neuropathic pain. Further observations and a larger group of patients are necessary for a reliable assessment of the effectiveness of neuromodulative treatment of chronic pain in our clinic.

摘要

背景与目的

神经调节治疗慢性疼痛综合征是治疗神经病理性和缺血性疼痛的一种现代治疗模式。其疗效在文献中有充分的记载。本研究的目的是基于我科 8 年的经验,介绍慢性疼痛综合征的治疗结果。

材料与方法

自 2002 年以来,我们在治疗慢性疼痛方面进行了 9 例运动皮层刺激(MCS)、2 例深部脑刺激(DBS)、45 例脊髓刺激(SCS)和 5 例骶神经根刺激(SRS)手术。

结果

我们在 MCS 治疗的 9 例患者中获得了 4 例(44%)、诊断为失败的腰椎手术综合征(FBSS)的 13 例、其他神经病理性疼痛的 8 例和心绞痛的 11 例患者的长期良好神经调节效果(临床改善>50%)。SCS 治疗的 45 例患者中,骶神经根刺激在 3 例肛门周围疼痛患者中取得了成功。SCS 治疗的最佳结果,尽管在统计学上无显著意义,但在 FBSS(13/15)和心绞痛(11/15)治疗的患者中观察到(p=0.12)。在周围和中枢神经病理性疼痛患者中,15 例患者中有 8 例得到了改善。

结论

脊髓刺激的良好适应证是 FBSS 和心绞痛。运动皮层刺激有助于治疗慢性中枢性神经病理性疼痛。对于我们诊所慢性疼痛神经调节治疗效果的可靠评估,需要进一步观察和更大的患者群体。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验