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用边缘白质切除术治疗 Gilles de la Tourette 综合征。

The treatment of Gilles de la Tourette syndrome by limbic leucotomy.

作者信息

Robertson M, Doran M, Trimble M, Lees A J

机构信息

Department of Neurology, National Hospital for Nervous Diseases, London.

出版信息

J Neurol Neurosurg Psychiatry. 1990 Aug;53(8):691-4. doi: 10.1136/jnnp.53.8.691.

DOI:10.1136/jnnp.53.8.691
PMID:2213047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC488174/
Abstract

A patient with Gilles de la Tourette syndrome and severe self-injurious compulsions who had failed to respond to drug treatment and behavioural therapy obtained a complete and sustained resolution of his destructive behaviour and improvement in his tics following bilateral limbic leucotomy.

摘要

一名患有 Gilles de la Tourette 综合征且有严重自残强迫行为的患者，药物治疗和行为疗法均无效，在接受双侧边缘叶白质切除术后，其破坏性行为完全且持续缓解，抽动症状也有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eec/488174/453b519f5c74/jnnpsyc00518-0064-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eec/488174/f737c4b734b4/jnnpsyc00518-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eec/488174/453b519f5c74/jnnpsyc00518-0064-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eec/488174/f737c4b734b4/jnnpsyc00518-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eec/488174/453b519f5c74/jnnpsyc00518-0064-b.jpg

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The treatment of Gilles de la Tourette syndrome by limbic leucotomy.用边缘白质切除术治疗 Gilles de la Tourette 综合征。
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本文引用的文献

1
Gilles de la Tourette Syndrome Treated by Bimedial Frontal Leucotomy.双侧额叶白质切断术治疗抽动秽语综合征
Can Med Assoc J. 1962 Apr 21;86(16):746-7.
2
Anterior cingulectomy in the treatment of mental disease.前扣带回切除术治疗精神疾病。
Lancet. 1952 Mar 8;1(6706):475-81. doi: 10.1016/s0140-6736(52)90051-2.
3
THE SYNDROME OF GILLES DE LA TOURETTE AND ITS TREATMENT: REPORT OF A CASE.Gilles de la Tourette综合征及其治疗：一例报告。
一种新的基于局部场电位的功能方法，用于靶向中央中缝核-旁正中复合体进行深部脑刺激。
Neuroimage Clin. 2021;30:102644. doi: 10.1016/j.nicl.2021.102644. Epub 2021 Mar 26.
4
Lead Repositioning Guided by Both Physiology and Atlas Based Targeting in Tourette Deep Brain Stimulation.基于生理和基于 atlas 靶点的引导在图雷特氏症深部脑刺激中的重新定位。
Tremor Other Hyperkinet Mov (N Y). 2020 Jul 8;10:18. doi: 10.5334/tohm.140.
5
Differentiating tic electrophysiology from voluntary movement in the human thalamocortical circuit.在人类丘脑皮质回路中区分抽动的电生理学与随意运动。
J Neurol Neurosurg Psychiatry. 2020 May;91(5):533-539. doi: 10.1136/jnnp-2019-321973. Epub 2020 Mar 5.
6
[Surgery for behavioral disorders: the state of the art].[行为障碍的外科治疗：当前技术水平]
Surg Neurol Int. 2014 Aug 4;5(Suppl 5):S211-31. doi: 10.4103/2152-7806.137936. eCollection 2014.
7
Swearing, euphemisms, and linguistic relativity.咒骂、委婉语和语言相对论。
PLoS One. 2011;6(7):e22341. doi: 10.1371/journal.pone.0022341. Epub 2011 Jul 20.
8
Neurosurgical strategies for Gilles de la Tourette's syndrome.神经外科治疗 Gilles de la Tourette 综合征的策略。
Neuropsychiatr Dis Treat. 2008 Dec;4(6):1111-28. doi: 10.2147/ndt.s4160.
9
Gilles de la Tourette's syndrome and its impact in the UK.Gilles de la Tourette综合征及其在英国的影响。
Postgrad Med J. 2005 Jan;81(951):12-9. doi: 10.1136/pgmj.2004.023614.
10
Pharmacological options for the treatment of Tourette's disorder.治疗抽动秽语综合征的药理学选择。
Drugs. 2001;61(15):2207-20. doi: 10.2165/00003495-200161150-00005.
Med Ann Dist Columbia. 1964 Jun;33:277-9.
4
[Stereotaxic treatment of tics and inarticulate cries or coprolalia considered as motor obsessional phenomena in Gilles de la Tourette's disease].[立体定向治疗抽动秽语综合征中被视为运动性强迫现象的抽搐、口齿不清的叫声或秽语症]
Rev Neurol (Paris). 1970 Aug;123(2):89-100.
5
Stereotactic limbic leucotomy: surgical technique.立体定向边缘白质切断术：手术技术
Postgrad Med J. 1973 Dec;49(578):860-4. doi: 10.1136/pgmj.49.578.860.
6
Experiences with dentatotomy.齿状切开术的经验
Confin Neurol. 1972;34(5):320-4. doi: 10.1159/000103076.
7
The cingulate gyrus and human behaviour.
Electroencephalogr Clin Neurophysiol. 1973 Jan;34(1):45-52. doi: 10.1016/0013-4694(73)90149-1.
8
Naloxone in Gilles de la Tourette's syndrome.纳洛酮治疗抽动秽语综合征。
Ann Neurol. 1987 Apr;21(4):415. doi: 10.1002/ana.410210421.
9
The inheritance of Gilles de la Tourette's syndrome and associated behaviors. Evidence for autosomal dominant transmission.抽动秽语综合征及相关行为的遗传。常染色体显性遗传的证据。
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10
Structural and functional studies of Gilles de la Tourette syndrome.
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