Poljak Mario
Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia.
Acta Dermatovenerol Alp Pannonica Adriat. 2011 Sep;20(3):99-112.
Human papillomaviruses (HPV), remarkably diverse DNA viruses etiologically linked with various benign and malignant neoplastic lesions of mucosal and skin epithelium have been the subject of intensive research for the last 30 years worldwide.
Briefly to review 20 years of HPV research in Slovenia by analyzing the articles published in journals indexed in peer-reviewed databases Medline/Pubmed, Science Citation Index/Web of Science, Embase and PsycINFO.
Up until October 2011, Slovenian researchers published 73 articles in journals indexed in peer-reviewed databases, which can be divided into 15 categories: detection of HPV in archival clinical specimens, development of novel HPV tests, evaluation of various commercial tests for the detection of high- and low-risk alpha-HPV, HPV and anogenital tumours, HPV testing in routine gynecological practice, HPV and laryngeal benign tumours, HPV and laryngeal epithelial hyperplastic lesions and laryngeal cancer, HPV and tumors in oral cavity, HPV and esophageal benign and malignant tumors, HPV and inverted papillomas, genomic diversity of selected HPV types, hair follicles as an important endogenous reservoir of HPV, identification and characterization of novel HPV types, HPV vaccination and HPV basic research. Until October 2011, Slovenian HPV papers received 473 citations (self-citation excluded) and their Hirsch index is currently h=13.
In the last 20 years, Slovenian HPV researchers have been actively and successfully incorporated in the international HPV community and have contributed small but significant achievements in the field.
人乳头瘤病毒(HPV)是一类极具多样性的DNA病毒,在病因学上与黏膜和皮肤上皮的各种良性及恶性肿瘤性病变相关联。在过去30年里,它一直是全球深入研究的对象。
通过分析发表在同行评审数据库Medline/Pubmed、科学引文索引/科学网、Embase和PsycINFO中索引期刊上的文章,简要回顾斯洛文尼亚20年的HPV研究情况。
截至2011年10月,斯洛文尼亚研究人员在同行评审数据库索引的期刊上发表了73篇文章,可分为15类:存档临床标本中HPV的检测、新型HPV检测方法的开发、各种检测高危和低危α-HPV商业检测方法的评估、HPV与肛门生殖器肿瘤、常规妇科实践中的HPV检测、HPV与喉良性肿瘤、HPV与喉上皮增生性病变及喉癌、HPV与口腔肿瘤、HPV与食管良性和恶性肿瘤、HPV与内翻性乳头状瘤、特定HPV类型的基因组多样性、毛囊作为HPV重要的内源性储存库、新型HPV类型的鉴定与特征分析、HPV疫苗接种及HPV基础研究。截至2011年10月,斯洛文尼亚HPV相关论文共获得473次引用(排除自引),其Hirsch指数目前为h = 13。
在过去20年里,斯洛文尼亚HPV研究人员积极且成功地融入了国际HPV研究群体,并在该领域取得了虽小但意义重大的成就。