Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208031, 300 Cedar St., New Haven, CT 06520-8031, USA.
FASEB J. 2011 Dec;25(12):4073-8. doi: 10.1096/fj.11-1201ufm.
This is a discussion of acute gouty arthritis, seen for over 50 years of engagement. It addresses the evolution of our current understanding of the interaction between urate crystals and key cellular components of the gouty inflammatory paroxysm, with new material on pathogenesis.
这是一篇关于急性痛风性关节炎的讨论,作者从事相关工作已超过 50 年。本文探讨了我们目前对尿酸盐晶体与痛风炎症发作关键细胞成分相互作用的理解的演变,并提供了发病机制方面的新材料。