Diabetic Foot Unit, Carlos Haya University Hospital, Malaga, Spain.
Diabetes Res Clin Pract. 2012 Mar;95(3):399-405. doi: 10.1016/j.diabres.2011.10.035. Epub 2011 Nov 30.
We studied the changes in the incidence of lower limb amputation (LLA) in Andalusia from 1998 to 2006 in the population with and without diabetes.
We undertook a retrospective study of all LLA performed in Andalusia in people aged 30 years old, with or without diabetes, between 1 January 1998 and 31 December 2006. We obtained the crude and standardized incidence rates by year, and sex for three periods: 1998-2000, 2001-2003 and 2004-2006 and calculated the RR of requiring LLA in patients with diabetes. To test for time trend, Poisson regression models were fitted.
A total of 16,210 LLA were carried out in Andalusia, 72.6% in patients with diabetes mellitus and 66.4% in men. In the population with diabetes the standardized incidence of all LLA was found to be 344.0 per 100,000 (95% CI, 315.4-372.4) in 2004-2006. There was an estimated incidence increase for all LLA by 14% and for minor LLA by 13.6% in 2004-2006. In people with diabetes the RR increased by 31.6% as compared to the first period.
Despite the implementation of a care plan for patients with diabetes, the incidence of LLA has not fallen in Andalusia in recent years.
我们研究了 1998 年至 2006 年期间安达卢西亚地区有和无糖尿病人群下肢截肢(LLA)发病率的变化。
我们对 1998 年 1 月 1 日至 2006 年 12 月 31 日期间安达卢西亚地区年龄在 30 岁及以上、有和无糖尿病的所有 LLA 患者进行了回顾性研究。我们按年和性别获得了三个时期(1998-2000 年、2001-2003 年和 2004-2006 年)的粗发病率和标准化发病率,并计算了糖尿病患者需要 LLA 的 RR。为了检验时间趋势,我们拟合了 Poisson 回归模型。
安达卢西亚共进行了 16210 例 LLA,72.6%的患者患有糖尿病,66.4%为男性。在糖尿病患者中,2004-2006 年所有 LLA 的标准化发病率为 344.0/100000(95%CI,315.4-372.4)。与前两个时期相比,2004-2006 年所有 LLA 的估计发病率增加了 14%,小截肢的发病率增加了 13.6%。与第一个时期相比,糖尿病患者的 RR 增加了 31.6%。
尽管为糖尿病患者实施了护理计划,但近年来安达卢西亚的 LLA 发病率并未下降。