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Analysis of viral gene functions by means of early temperature-sensitive mutants of human cytomegalovirus.

作者信息

Ihara S, Hirai K, Watanabe Y

出版信息

IARC Sci Publ (1971). 1978(24 Pt 1):365-71.

PMID:221341
Abstract

Fifteen ts mutants of CMV, which are unable to form normal plaques at 39 degrees C on HEL cells but do form plaques at 34 degrees C, have been isolated following mutagenesis by ultraviolet light. Five mutants defective in viral DNA synthesis at 39 degrees C were divided into two different complementation groups and examined for various phenotypic characteristics.

摘要

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