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儿童钝性脾损伤和肝损伤保守非手术治疗中的输血需求

Transfusion requirements in conservative nonoperative management of blunt splenic and hepatic injuries during childhood.

作者信息

Cosentino C M, Luck S R, Barthel M J, Reynolds M, Raffensperger J G

机构信息

Department of Surgery, Children's Memorial Medical Center, Northwestern University Medical School, Chicago, IL 60614.

出版信息

J Pediatr Surg. 1990 Sep;25(9):950-3; discussion 953-4. doi: 10.1016/0022-3468(90)90236-3.

Abstract

Nonoperative management of splenic and hepatic injuries in children is safe, and the majority of those with isolated injuries do not require blood transfusion. Thirty-seven children were treated for blunt splenic or hepatic trauma from November 1983 to September 1989. There was one death in a patient with a lethal head injury. No operations were performed on those with isolated splenic or hepatic injuries. Three of those with multiple injuries underwent delayed laparotomy. Two had perirenal and retroperitoneal hematomas without active bleeding, and one had a bowel obstruction secondary to an intramural jejunal hematoma. There were no late complications related to the splenic or hepatic injuries. Eight children (22%) required surgery for other injuries. Twelve children were not transfused, including the majority (8/11) of those with isolated splenic or hepatic injury. The hematocrit of four of these children fell to below 28% and this anemia was well-tolerated. Two children with bleeding disorders (factor VIII [antihemophilic factor] and factor XII [Hageman factor] deficiency) did not require packed red blood cells transfusion. Two clinically distinct groups of children received blood transfusions: (1) eight patients with multiple injuries were transfused during initial resuscitation when unstable or during early operation for other system trauma (mean, 62.0 mL blood/kg body weight); and (2) three hemodynamically stable patients with isolated injuries and 14 stable patients with multiple injuries were transfused empirically after initial resuscitation solely because of decreasing blood counts. They received an average of 16.5 and 21.1 mL blood/kg body weight, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

儿童脾损伤和肝损伤的非手术治疗是安全的,大多数单纯损伤患儿不需要输血。1983年11月至1989年9月,37例儿童因钝性脾或肝外伤接受治疗。1例合并致命性颅脑损伤的患者死亡。单纯脾或肝损伤患儿均未接受手术治疗。3例多发伤患儿接受了延迟剖腹手术。2例有肾周和腹膜后血肿但无活动性出血,1例因空肠壁内血肿继发肠梗阻。未出现与脾或肝损伤相关的晚期并发症。8例儿童(22%)因其他损伤需要手术治疗。12例儿童未输血,包括大多数(8/11)单纯脾或肝损伤患儿。其中4例儿童的血细胞比容降至28%以下,这种贫血情况耐受性良好。2例患有出血性疾病(因子VIII[抗血友病因子]和因子XII[哈格曼因子]缺乏)的儿童不需要输注浓缩红细胞。有两组临床表现不同的儿童接受了输血:(1)8例多发伤患者在初始复苏不稳定时或因其他系统创伤早期手术期间接受输血(平均,62.0 mL/kg体重);(2)3例血流动力学稳定的单纯损伤患者和14例血流动力学稳定的多发伤患者在初始复苏后仅凭血细胞计数下降接受经验性输血。他们分别平均接受了16.5和21.1 mL/kg体重的输血。(摘要截选至250字)

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