Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY.
Am J Clin Oncol. 2013 Dec;36(6):630-6. doi: 10.1097/COC.0b013e31822dfd71.
Stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS) for spinal metastases are emerging treatment paradigms in the multidisciplinary management of metastases located within or adjacent (paraspinal) to the vertebral bodies/spinal cord. In this review, we provide a brief overview of spine SBRT/SRS indications, technology, planning, and treatment delivery; review the current state of the literature; and discuss the radiobiology, toxicity, and limitations of SBRT/SRS for metastatic disease of the spine.
立体定向体部放射治疗(SBRT)和立体定向放射外科(SRS)是脊柱转移瘤多学科治疗中新兴的治疗模式,适用于位于椎体/脊髓内部或邻近(椎旁)的转移瘤。在本文中,我们简要概述了脊柱 SBRT/SRS 的适应证、技术、计划和治疗实施;回顾了目前的文献状况;并讨论了脊柱转移瘤 SBRT/SRS 的放射生物学、毒性和局限性。