Bowden Patrick J, See Andrew W, Dally Michael J, Bittar Richard G
Epworth Healthcare, Melbourne, VIC, Australia; Brain and Spine Tumour Clinic, Melbourne, VIC, Australia.
Epworth Healthcare, Melbourne, VIC, Australia; Monash University, Clayton, Melbourne, VIC, Australia.
J Clin Neurosci. 2014 May;21(5):731-4. doi: 10.1016/j.jocn.2013.07.043. Epub 2013 Nov 9.
Metastases to the brain and spine are common and difficult to treat. Stereotactic radiosurgery (SRS) is a non-invasive treatment option for some individuals, and may obviate the need for open surgery and/or whole brain radiotherapy. Over the past decade there has been an increased number of patients undergoing SRS for the treatment of metastatic disease, and multiple published studies show favourable results in terms of local disease control. We review the available literature pertaining to the application of SRS for the treatment of brain and spine metastases, together with its limitations and outcomes.
脑和脊柱转移瘤很常见且难以治疗。立体定向放射外科(SRS)是一些患者的非侵入性治疗选择,可能无需进行开放手术和/或全脑放疗。在过去十年中,接受SRS治疗转移性疾病的患者数量有所增加,多项已发表的研究显示在局部疾病控制方面有良好结果。我们回顾了有关SRS用于治疗脑和脊柱转移瘤的现有文献,以及其局限性和治疗结果。