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Stereochemical studies of the type II isopentenyl diphosphate-dimethylallyl diphosphate isomerase implicate the FMN coenzyme in substrate protonation.

作者信息

Calveras Jordi, Thibodeaux Christopher J, Mansoorabadi Steven O, Liu Hung-wen

机构信息

Division of Medicinal Chemistry, College of Pharmacy, Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, TX 78712, USA.

出版信息

Chembiochem. 2012 Jan 2;13(1):42-6. doi: 10.1002/cbic.201100694. Epub 2011 Dec 1.

Abstract
摘要

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The lycopene cyclase CrtY from Pantoea ananatis (formerly Erwinia uredovora) catalyzes an FADred-dependent non-redox reaction.
J Biol Chem. 2010 Apr 16;285(16):12109-20. doi: 10.1074/jbc.M109.091843. Epub 2010 Feb 23.
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J Biol Chem. 2009 Apr 3;284(14):9160-7. doi: 10.1074/jbc.M808438200. Epub 2009 Jan 21.
6
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