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[小儿肋骨尤文肉瘤:新辅助化疗在肿瘤缩小和清除中的作用。病例报告]

[Pediatric Ewing sarcoma of the rib: role of neoadjuvant chemotherapy in tumoral shrinking and sterilization. A case report].

作者信息

Zidane A, Traibi A, Arsalane A, Atoini F, Ouriachi F, Hammoumi M, Kabiri E H

机构信息

Service de chirurgie thoracique, hôpital militaire d'instruction Mohamed V, Rabat, Maroc.

出版信息

Rev Pneumol Clin. 2011 Dec;67(6):371-4. doi: 10.1016/j.pneumo.2011.01.005. Epub 2011 Apr 29.

Abstract

Ewing sarcoma is a rare tumor, which represents, nevertheless, the most common primary chest wall tumor in children. The management and prognosis of these tumors have markedly improved with the use of multimodal therapy including adjuvant chemotherapy, surgery and/or irradiation. A good response to chemotherapy often avoids the need for extensive local treatment without sacrificing local control or long-term survival. Here, we report a new case of a bulky rib Ewing sarcoma, well managed by neoadjuvant chemotherapy resulting in significantly tumor shrinking that allowed complete resection. At the histological examination of the specimen, there was only inflammatory and fibrosis tissues without viable tumoral tissue.

摘要

尤因肉瘤是一种罕见的肿瘤,但却是儿童中最常见的原发性胸壁肿瘤。通过采用包括辅助化疗、手术和/或放疗在内的多模式治疗,这些肿瘤的治疗和预后有了显著改善。对化疗的良好反应通常可避免在不牺牲局部控制或长期生存的情况下进行广泛的局部治疗。在此,我们报告一例巨大肋骨尤因肉瘤的新病例,通过新辅助化疗得到了良好的治疗,肿瘤显著缩小,从而得以完整切除。在标本的组织学检查中,仅见炎性和纤维化组织,未见存活的肿瘤组织。

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