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经典气管内导管、双腔管和喉罩气道放置后的心血管变化。

Cardiovasular changes after placement of a classic endotracheal tube, double-lumen tube, and Laryngeal Mask Airway.

机构信息

Department of Anaesthesiology and Reanimation, Gaziantep University School of Medicine, 27310 Sahinbey, Gaziantep, Turkey.

出版信息

J Clin Anesth. 2011 Dec;23(8):616-20. doi: 10.1016/j.jclinane.2011.03.005.

Abstract

STUDY OBJECTIVE

To compare hemodynamic responses, P wave dispersion (Pd), and QT dispersion (QTd) after placement of a classic endotracheal tube (ETT), double-lumen tube (DLT), or Laryngeal Mask Airway (LMA).

DESIGN

Prospective study.

SETTING

Outpatient surgery center.

PATIENTS

75 adult, ASA physical status 1 and 2 patients undergoing cystoscopy and thoracoscopic surgery.

INTERVENTIONS

Patients were randomized to undergo placement of an ETT (Group T; n = 25), DLT (Group D; n = 25), or LMA (Group L; n = 25). Anesthesia was induced by etomidate 0.3 mg/kg and fentanyl 1.0 μg/kg, and maintained with nitrous oxide, oxygen, 2% to 3% sevoflurane, and rocuronium 0.5 mg/kg.

MEASUREMENTS

Mean arterial pressure (MAP) and heart rate (HR) were recorded immediately before intubation and after intubation at one, 3, 5, 10,15, 20, 25, and 30 minutes after intubation/airway insertion.

RESULTS

QT dispersion after tube placement was significantly higher than before tube placement in Group D (P = 0.0001) and Group L (P = 0.03). Mean arterial pressure and HR in Group T were significantly higher than in Group L at the first minute after tube placement (P = 0.02). Heart rate and MAP at baseline were significantly higher than the other measurement times in Groups T and D (P < 0.01).

CONCLUSIONS

The LMA caused no change in Pd, HR, or MAP values during or after airway placement, but caused QTd after airway insertion. The ETT caused a sudden increase at the first minute after tube placement, without any Pd or QTd. In addition, DLT caused QTd without any serious change in hemodynamics.

摘要

研究目的

比较经典气管内导管(ETT)、双腔管(DLT)和喉罩气道(LMA)置入后血流动力学反应、P 波离散度(Pd)和 QT 离散度(QTd)。

设计

前瞻性研究。

地点

门诊手术中心。

患者

75 例美国麻醉医师协会(ASA)身体状况 1 级和 2 级行膀胱镜和胸腔镜手术的成年患者。

干预

患者随机分为 ETT 组(T 组,n=25)、DLT 组(D 组,n=25)或 LMA 组(L 组,n=25)。麻醉诱导用依托咪酯 0.3mg/kg 和芬太尼 1.0μg/kg,维持用氧化亚氮、氧气、2%~3%七氟醚和罗库溴铵 0.5mg/kg。

测量

在插管前和插管后 1、3、5、10、15、20、25 和 30 分钟记录平均动脉压(MAP)和心率(HR)。

结果

与 D 组(P=0.0001)和 L 组(P=0.03)相比,DLT 组和 LMA 组在置管后 QTd 显著升高。T 组在置管后 1 分钟时的 MAP 和 HR 明显高于 L 组(P=0.02)。T 组和 D 组的 HR 和 MAP 在基线时明显高于其他测量时间(P<0.01)。

结论

LMA 在气道置入过程中和置入后不会改变 Pd、HR 或 MAP 值,但会导致气道置入后 QTd。ETT 在置管后第 1 分钟会突然增加,而无 Pd 或 QTd。此外,DLT 会导致 QTd,而血流动力学无明显变化。

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